Table 2.
Main drug-induced TMA
| Cancer therapies | Immunosuppressants | Others |
|---|---|---|
|
Cytotoxic agents: gemcitabine, mytomicin C |
Calcineurin inhibitors: cyclosporine, tacrolimus |
Biological agents: adalimumab, imatinib |
|
VEGF inhibitors: bevacizumab, sunitinib |
m-TOR inhibitors: sirolimus, everolimus |
Antibiotics: ciprofloxacin, metronidazole, nitrofurantoin, trimethoprim/sulfamethoxazole |
|
Proteasome inhibitors: bortezomib, carfilzomib |
Commonly used drugs: ibuprofen, ketorolac, clopidogrel, simvastatin, oestrogen/progesterone |