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Genetic and acquired complement abnormalities in aHUS
| Complement regulatory factors | Complement activation factors | Coagulation- related factors |
|---|---|---|
| CFH | C3 | THBD |
| CFH/CFHR hybrid gene | CFB | DGKE |
| CFI | PLG | |
| MCP | ||
| Anti-CFHantibodies |
CFHR, complement factor H related; CFI, complement factor I; MCP, membrane cofactor protein; C3, complement component C3; CFB, complement factor B; THBD, thrombomodulin; DGKE, diacylglycerol kinase epsilon; PLG, plasminogen.
