Table 3.
Univariate regression analysis of clinical variables vs MSK-BFI and LARS-Q scores in the study cohort
| Characteristic | MSK-BFI | LARS Total | ||||
|---|---|---|---|---|---|---|
| Estimate | 95% CI | p value | Estimate | 95% CI | p value | |
| Age | −0.079 | −0.23 to 0.07 | 0.313 | −0.027 | −0.084 to 0.137 | 0.635 |
| Male vs female | 2.077 | −1.28 to 5.43 | 0.225 | −0.049 | −2.481 to 2.383 | 0.968 |
| Tumour distance from the anal verge | 1.110 | 0.56 to 1.66 | <0.0001 | −0.557 | −0.961 to −0.152 | 0.007 |
| Clinical AJCC stage | ||||||
| I vs III | 2.894 | −1,68 to 7.47 | 0.215 | −0.337 | −3.654 to 2.979 | 0.842 |
| II vs III | −0.664 | −5.18 to 3.85 | 0.773 | 0.490 | −2.787 to 3.766 | 0.770 |
| Chemoradiation (yes vs no) | −3.097 | −6.44 to 0.25 | 0.070 | 1.915 | −0.508 to 4.339 | 0.121 |
| Surgical approach | ||||||
| Robotic vs open | −1.012 | −5.35 to 3.32 | 0.647 | 0.298 | −2.820 to 3.416 | 0.851 |
| Laparoscopic vs open | −0.533 | −7.66 to 6.59 | 0.883 | 2.614 | −7.873 to 2.373 | 0.293 |
| Handsewn anastomosis (yes vs no) | −9-090 | −13.81 to −4.37 | <0.001 | 3.512 | 0.012 to 7.012 | 0.049 |
| Diverting loop ileostomy (yes vs no) | −5.803 | 9.64 to −1.96 | 0.003 | 2.406 | −0.410 to 5.222 | 0.094 |
| Pathological AJCC stage | ||||||
| 0/Tis vs III | −0.050 | −4.99 to 4.89 | 0.984 | −1.381 | −4.999 to 2.237 | 0.454 |
| I vs III | 4.026 | −0.21 to 8.26 | 0.062 | −1.929 | −5.030 to 1.173 | 0.223 |
| II vs III | 6.610 | 1.42 to 11.8 | 0.013 | −3.692 | −7.493 to 0.109 | 0.057 |
| Postoperative complications | −4.119 | −8,10 to −0,14 | 0.042 | 0.613 | −2.290 to 3.515 | 0.679 |
| Anastomotic leak | 0.412 | −6.79 to 7.62 | 0.911 | −3.370 | −8.551 to 1.81 | 0.202 |
Abbreviations: AJCC, American Joint Committee on Cancer.