Table 1.
Perioperative Characteristics of Younger (Age ≤73 Years) Versus Older (Age >73 Years) Patients Undergoing Esophagectomy Stratified Based on Age Cutoff Identified Through Maximally Selected Rank Statisticsa
| Characteristic | Younger (n = 10,122) |
Older (n = 1558) |
P |
|---|---|---|---|
| Age y | 62 (55-67) | 77 (75-79) | N/A |
| Sex (female) | 1107 (11) | 221 (14) | <.001 |
| Race | .07 | ||
| White | 9785 (98) | 1512 (98) | |
| Black | 144 (1) | 12 (1) | |
| Other | 109 (1) | 21 (1) | |
| Year of diagnosis | 2010 (2008-2013) | 2010 (2008-2013) | .28 |
| Charlson-Deyo score | <.001 | ||
| 0 | 7476 (74) | 1066 (68) | |
| 1 | 2125 (21) | 388 (25) | |
| ≥2 | 521 (5) | 104 (7) | |
| Insurance status | <.001 | ||
| Private | 5583 (56) | 144 (9) | |
| Government | 4123 (42) | 1384 (90) | |
| None | 203 (2) | 8 (1) | |
| Facility location | .61 | ||
| Metropolitan | 7721 (79) | 1188 (80) | |
| Urban | 1795 (18) | 260 (18) | |
| Rural | 232 (2) | 39 (2) | |
| Distance to treatment center, miles | 19 (8-49) | 17 (7-48) | .04 |
| Facility type | .006 | ||
| Academic/research | 5409 (54) | 788 (51) | |
| Annualized center surgical volume, cases/y | 7 (2-17) | 6 (2-14) | .11 |
| Clinical stage | <.001 | ||
| II | 5091 (50) | 926 (59) | |
| III | 5031 (50) | 632 (41) | |
| Distal primary tumor | 8743 (86) | 1339 (86) | .67 |
| Tumor size, mm | 40 (25-55) | 40 (25-53) | .39 |
| Minimally invasive approach | 1559 (15) | 265 (17) | .11 |
| Neoadjuvant therapies | |||
| Neoadjuvant chemotherapy | 8915 (89) | 1063 (69) | <.001 |
| Neoadjuvant radiation | 8587 (85) | 998 (64) | <.001 |
| Length of stay, d | 9 (7-14) | 10 (8-17) | <.001 |
| Unplanned 30-d readmission | 531 (5) | 98 (6) | .10 |
| Positive margins | 576 (6) | 125 (8) | <.001 |
| 30-d mortality | 265 (3) | 113 (7) | <.001 |
| 90-d mortality | 643 (6) | 228 (15) | <.001 |
a
All values are n (%) or median (interquartile range) unless otherwise stated.
N/A, not applicable.