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. Author manuscript; available in PMC: 2021 Apr 6.
Published in final edited form as: JACC Heart Fail. 2017 Oct;5(10):724–734. doi: 10.1016/j.jchf.2017.07.013

Table 2:

Association of GDF-15 with baseline clinical and biomarker variables

Variable Coefficient 95% Confidence Limits T P-value

Log-2(hsTnT) 0.18 (0.12, 0.23) 6.32 <.0001
Age, years 0.01 (0.01, 0.02) 5.86 <.0001
Peak VO2, mL/kg/min −0.04 (−0.06, −0.03) −5.69 <.0001
Log-2(creatinine) 0.35 (0.22, 0.48) 5.25 <.0001
Log-2(NT-proBNP) 0.08 (0.05, 0.12) 4.39 <.0001
LVEF, % 0.01 (0.007, 0.02) 3.75 0.0002
SBP, mmHg for values up to 125 −0.008 (−0.01, −0.003) −3.49 0.0005
SBP, mmHg for values above 125 0.008 (0.002, 0.01) 2.47 0.0136
White race 0.19 (0.08,0.31) 3.29 0.0011
BMI, for values up to 35 −0.02 (−0.03,−0.008) −3.20 0.0015
Blood urea nitrogen (mg/dL) 0.007 (0.002, 0.01) 2.98 0.0030
Diabetes 0.17 (0.06, 0.28) 2.96 0.0032
Heart rate, beats per min 0.006 (0.001, 0.01) 2.64 0.0086
NYHA class III/IV 0.12 (0.01, 0.23) 2.19 0.0292