Table 1. Mean AUROC scores for the Dash data using leave-one-subject-out cross-validation.

TCRGP models and TCRdist models were trained using either only CDR3s or all CDRs from TCRαβ, TCRβ, or TCRα.

	Method	TCRGP						TCRdist
	chains	αβ		β		α		αβ		β		α
	cdrs	3	all	3	all	3	all	3	all	3	all	3	all
	mean	0.871	0.913	0.830	0.883	0.823	0.856	0.834	0.828	0.807	0.797	0.781	0.732
EBV	BMLF1280-288	0.876	0.906	0.818	0.877	0.862	0.877	0.875	0.830	0.816	0.774	0.821	0.778
CMV	pp65495-503	0.702	0.821	0.587	0.871	0.759	0.787	0.645	0.691	0.636	0.670	0.672	0.822
IAV	M158-66	0.781	0.833	0.782	0.834	0.769	0.768	0.769	0.768	0.774	0.729	0.716	0.686
IAV	PB1-F262-70	0.847	0.937	0.822	0.803	0.753	0.801	0.820	0.862	0.802	0.753	0.729	0.636
IAV	NP366-374	0.906	0.928	0.897	0.907	0.821	0.847	0.874	0.818	0.841	0.788	0.781	0.709
IAV	PA224-233	0.952	0.975	0.939	0.961	0.882	0.930	0.914	0.914	0.887	0.862	0.869	0.777
IAV	PB1703-711	0.929	0.953	0.913	0.919	0.862	0.929	0.913	0.819	0.901	0.844	0.849	0.711
mCMV	m139419-426	0.877	0.888	0.721	0.806	0.844	0.821	0.773	0.785	0.656	0.779	0.769	0.683
mCMV	M38316-323	0.926	0.922	0.917	0.924	0.868	0.902	0.921	0.918	0.920	0.914	0.844	0.789
mCMV	M45985-993	0.920	0.962	0.891	0.923	0.851	0.916	0.876	0.879	0.846	0.838	0.796	0.772