Skip to main content
. 2021 Mar 25;17(3):e1008814. doi: 10.1371/journal.pcbi.1008814

Table 3. Datasets.

Dash data: The data set constructed by Dash et al. [10] contains epitope-spcefic TCRs for Epstein-Barr virus (EBV), human Cytomegalovirus (CMV), Influenza A virus (IAV) and mouse Cytomegalovirus (mCMV). VDJdb data: Data set gathered from VDJdb contains epitope-specific TCRs for Cytomegalovirus (CMV), Epstein-Barr virus (EBV), Influenza A virus (IAV), Hepatitis C virus (HCV), Herpes Simplex virus type 2 (HSV-2), Yellow Fever virus (YFV), Dengue virus type 1 (DENV1), Dengue virus type 3 (DENV3-4), and Human immunodeficiency virus type 1 (HIV-1). For the MHC chains we show here only the allele group. For some epitopes there are TCRs for which there exists more detailed information and some variation, which are shown in S3 File.

Dash data
Species Epitope species Epitope gene Epitope MHC chain 1 MHC chain 2 Subjects Samples Unique TCRαβs
Human EBV BMLF1280-288 GLCTLVAML HLA-A*02:01 - 6 76 69
CMV pp65495-503 NLVPMVATV HLA-A*02:01 - 10 61 60
IAV M158-66 GILGFVFTL HLA-A*02:01 - 15 275 237
Mouse IAV PB1-F262-70 LSLRNPILV Db - 9 117 117
IAV NP366-374 ASNENMETM Db - 24 305 263
IAV PA224-233 SSLENFRAYV Db - 15 324 293
IAV PB1703-711 SSYRRPVGI Kb - 34 642 584
mCMV m139419-426 TVYGFCLL Kb - 8 87 87
mCMV M38316-323 SSPPMFRV Kb - 14 158 143
mCMV M45985-993 HGIRNASFI Db - 13 291 271
VDJdb data
Human CMV pp65123-131 IPSINVHHY HLA-B*35 B2M 17 65 58
CMV pp65417-426 TPRVTGGGAM HLA-B*07 B2M 29 184 122
CMV pp65495-503 NLVPMVATV HLA-A*02 B2M 103 413 242
EBV BMLF1280-288 GLCTLVAML HLA-A*02 B2M 54 299 152
EBV BZLF1190-197 RAKFKQLL HLA-B*08 B2M 17 225 149
EBV BRLF1109-117 YVLDHLIVV HLA-A*02 B2M 6 66 51
IAV M158-66 GILGFVFTL HLA-A*02 B2M 50 239 138
IAV HA306-318 PKYVKQNTLKLAT HLA-DRA*01 HLA-DRB1*01,04 11 56 50
HCV NS31073-1081 CINGVCWTV HLA-A*02 B2M 7 76 39
HCV NS31406-1415 KLVALGINAV HLA-A*02 B2M 4 65 65
HCV NS31436-1445 ATDALMTGY HLA-A*01 B2M 7 152 139
HSV-2 VP2249-57 RPRGEVRFL HLA-B*07 B2M 5 68 29
YFV NS4B214-222 LLWNGPMAV HLA-A*02 B2M 5 223 198
DENV1 NS3133-142 GTSGSPIVNR HLA-A*11 B2M 11 65 59
DENV3-4 NS3133-142 GTSGSPIINR HLA-A*11 B2M 8 51 46
HIV-1 p2430-40 KAFSPEVIPMF HLA-B*57 B2M 44 134 104
HIV-1 p2448-56 TPQDLNTML HLA-B*42,81 B2M 21 52 40
HIV-1 p24128-135 EIYKRWII HLA-B*08 B2M 12 81 60
HIV-1 p24131-140 KRWIILGLNK HLA-B*27 B2M 27 212 141
HIV-1 p24161-180 FRDYVDRFYKTLRAEQASQE HLA-DRA*01 HLA-DRB1*01,07,11,15, HLA-DRB5*01 17 141 95
HIV-1 p24223-231 GPGHKARVL HLA-B*07 B2M 1 62 53
HIV-1 Nef90-97 FLKEKGGL HLA-B*08 B2M 21 104 78