Table 1.
Demographic and clinical characteristics of the study participants
| Selected variables | All (n = 269) | ICU (n = 69) | Non-ICU (n = 200) | Dead (n = 25) | Alive (n = 244) |
|---|---|---|---|---|---|
| Sex (Male, %) | 155 (57.6) | 35 (50.7) | 120 (60.0) | 16 (64.0) | 139 (57.0) |
| Age; Median (IQR); years | 51 (33–65) | 54 (40–67) | 50 (31–64) | 56 (47–67) | 50 (31–65) |
| Duration from onset to sampling; Median (IQR); days | 5 (3–7) | 5 (4–8) | 5 (3–7) | 6 (4–9) | 5 (3–7) |
| Dead patients | 25 (9.3) | 23 (33.3) | 2 (1.0) | ||
| Comorbidities or conditions | 162 (60.2) | 45 (65.2) | 117 (58.5) | 19 (76.0) | 143 (58.6) |
| Lung disease | 34 (12.6) | 6 (8.7) | 28 (14.0) | 1 (4.0) | 33 (13.5) |
| Hypertension | 27 (10.0) | 10 (14.5) | 17 (8.5) | 3 (12.0) | 24 (9.8) |
| Diabetes mellitus | 24 (8.9) | 12 (17.4) | 12 (6.0) | 4 (16.0) | 20 (8.2) |
| Liver disease | 24 (8.9) | 5 (7.2) | 19 (9.5) | 4 (16.0) | 20 (8.2) |
| Cardiovascular disease | 22 (8.2) | 10 (14.5) | 12 (6.0) | 3 (12.0) | 19 (7.8) |
| Pregnancy | 19 (7.1) | 3 (4.3) | 16 (8.0) | 0 (0) | 19 (7.8) |
| Kidney disease | 19 (7.1) | 6 (8.7) | 13 (6.5) | 1 (4.0) | 18 (7.4) |
| Collagen disease | 11 (4.1) | 5 (7.2) | 6 (3.0) | 3 (12.0) | 8 (3.3) |
| Cancer | 9 (3.3) | 3 (4.3) | 6 (3.0) | 0 (0) | 9 (3.7) |
| Tuberculosis | 6 (2.2) | 2 (2.9) | 4 (2.0) | 1 (4.0) | 5 (2.0) |
| HBV/HCV | 6 (2.2) | 1 (1.4) | 5 (2.5) | 1 (4.0) | 5 (2.0) |
| Hematological disease*1 | 5 (1.9) | 5 (7.2) | 0 (0) | 4 (16.0) | 1 (0.4) |
| Bronchial asthma | 4 (1.5) | 3 (4.3) | 1 (0.5) | 0 (0) | 4 (1.6) |
| Immunosuppressive agent usage*2 | 4 (1.5) | 4 (5.8) | 0 (0) | 4 (16.0) | 0 (0) |
| Others | 16 (5.9) | 4 (5.8) | 12 (6.0) | 2 (8.0) | 14 (5.7) |
Data are presented as numbers (%). IQR interquartile range. *1: significant differences after Bonferroni correction between ICU and non-ICU patients (Fisher’s exact test, corrected significance level p = 0.0033). *1, *2: significant differences after Bonferroni correction between Dead and Alive patients. (Fisher’s exact test, corrected significance level p = 0.0033). ICU intensive care unit, HBV/HCV hepatitis B or hepatitis C