Figure 7.

Heatmap of proteins found in trapped urine samples versus non-trapped urine samples. Keratin proteins have been removed. The heatmap is column-normalized and the legend gives the z-score of each sample. Cluster I shows weaker signals in the trapped fraction, suggesting that these are solute proteins that have been washed away from the trap during the washing step. Cluster II shows stronger signals in the trapped fraction, suggesting that these are proteins originating from vesicles that have been enriched during the trapping step. Cluster III shows highly fluctuating signals, indicating that these are proteins that are close to the limit of detection.