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. 2021 Feb 11;61(3):1193–1203. doi: 10.1021/acs.jcim.0c01216

Table 9. MCC to Compare the Combined OSP + TPF Method Against the LIE Approach for the 14 Compounds in Table 8a.

site P1′ LIE OSP + TPF
E105 Ile 0.03 0.78
E105 Pro 0.00 0.31
G171 Ile 0.00 0.34
G171 Pro 0.29 0.56
a

For each combination of mutation site and P1′, OSP + TPF outperformed LIE.