Table 4.
HRs for the major outcomes in patients without hospitalisation after COVID-19 compared with those after influenza or other RTIs
|
COVID-19 vs influenza in patients without hospitalisation (N=96 803)* |
COVID-19 vs other RTI in patients without hospitalisation (N=183 731)* |
|||
|---|---|---|---|---|
| HR (95% CI) | p value | HR (95% CI) | p value | |
| Intracranial haemorrhage (any) | 1·87 (1·25–2·78) | 0·0013 | 1·38 (1·11–1·73) | 0·0034 |
| Intracranial haemorrhage (first) | 1·66 (0·88–3·14) | 0·082 | 1·63 (1·11–2·40) | 0·010 |
| Ischaemic stroke (any) | 1·80 (1·54–2·10) | <0·0001 | 1·61 (1·45–1·78) | <0·0001 |
| Ischaemic stroke (first) | 1·71 (1·26–2·33) | 0·0003 | 1·69 (1·38–2·08) | <0·0001 |
| Parkinsonism | 2·22 (0·98–5·06) | 0·028 | 1·20 (0·73–1·96) | 0·42 |
| Guillain-Barré syndrome | 0·90 (0·44–1·84) | 0·99 | 1·44 (0·85–2·45) | 0·10 |
| Nerve, nerve root, or plexus disorders | 1·69 (1·53–1·88) | <0·0001 | 1·23 (1·15–1·33) | <0·0001 |
| Myoneural junction or muscle disease | 3·46 (2·11–5·67) | <0·0001 | 2·69 (1·91–3·79) | <0·0001 |
| Encephalitis | 1·77 (0·86–3·66) | 0·095 | 2·29 (1·28–4·10) | 0·0046 |
| Dementia | 1·88 (1·27–2·77) | 0·0008 | 1·95 (1·55–2·45) | <0·0001 |
| Mood, anxiety, or psychotic disorder (any) | 1·49 (1·45–1·54) | <0·0001 | 1·18 (1·15–1·21) | <0·0001 |
| Mood, anxiety, or psychotic disorder (first) | 1·85 (1·72–1·99) | <0·0001 | 1·40 (1·32–1·48) | <0·0001 |
| Mood disorder (any) | 1·49 (1·43–1·55) | <0·0001 | 1·22 (1·19–1·26) | <0·0001 |
| Mood disorder (first) | 1·78 (1·61–1·96) | <0·0001 | 1·37 (1·27–1·47) | <0·0001 |
| Anxiety disorder (any) | 1·48 (1·43–1·54) | <0·0001 | 1·16 (1·13–1·19) | <0·0001 |
| Anxiety disorder (first) | 1·80 (1·67–1·94) | <0·0001 | 1·37 (1·30–1·45) | <0·0001 |
| Psychotic disorder (any) | 1·93 (1·63–2·28) | <0·0001 | 1·44 (1·27–1·62) | <0·0001 |
| Psychotic disorder (first) | 2·27 (1·56–3·30) | <0·0001 | 1·49 (1·15–1·93) | 0·0016 |
| Substance use disorder (any) | 1·26 (1·19–1·33) | <0·0001 | 1·11 (1·07–1·17) | <0·0001 |
| Substance use disorder (first) | 1·21 (1·05–1·38) | 0·0054 | 0·89 (0·81–0·97) | 0·013 |
| Insomnia (any) | 1·52 (1·42–1·63) | <0·0001 | 1·18 (1·12–1·24) | <0·0001 |
| Insomnia (first) | 2·06 (1·82–2·33) | <0·0001 | 1·51 (1·38–1·66) | <0·0001 |
| Any outcome | 1·47 (1·44–1·51) | <0·0001 | 1·16 (1·14–1·17) | <0·0001 |
| Any first outcome | 1·83 (1·71–1·96) | <0·0001 | 1·28 (1·23–1·33) | <0·0001 |
Details on cohort characteristics are presented in the appendix (pp 37–40). HR=hazard ratio. RTI=respiratory tract infection.
*
Matched cohorts.