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. Author manuscript; available in PMC: 2022 Apr 2.
Published in final edited form as: Circ Res. 2021 Apr 1;128(7):887–907. doi: 10.1161/CIRCRESAHA.121.318064

Figure 5: Renin cells possess a unique set of SEs that differentiate them from other cell types.

Figure 5:

Top: Renin cells share ninety-one super-enhancers, including the renin super-enhancer, which are absent in other 21 tissue types. Bottom: The renin super-enhancer (grey bar) located upstream of the coding region of the renin (Ren1) gene shows overlap of the ATAC-Seq profile (JG cells, recruited cells, and As4.1 cells) with the ChIP-Seq signals for H3K27Ac (recruited cells and As4.1 cells), MED1 (As4.1 cells) and Pol II (As4.1 cells). Modified from99