Table 1.
Characteristics of patients with ulcerative colitis in persistent symptomatic and endoscopic remission over two consecutive endoscopies, with ongoing remission or subsequent clinical relapse.
No relapse | Relapse | p-value | ||
---|---|---|---|---|
Number of patients | 72 | 17 | ||
Age, mean, [SD] | 47.8 [16.1] | 53.5 [20.1] | 0.25 | |
Female gender, frequency | 52.8% | 58.8% | 0.39 | |
Age at diagnosis, mean [SD] | 34.2 [15.6] | 34.2 [17.2] | 0.84 | |
Disease duration, median [IQR] | 11.5 [9.75] | 17 [13] | <0.05 | |
Extensive colitis [% of total] | 52.8% | 47.1% | 0.67 | |
Current biologic and/or immunomodulator use frequency | 84.7% | 52.9% | <0.05 | |
Previous biologic or immunomodulator use | 76.3% | 70.6% | 0.62 | |
Duration of remission between endoscopic assessments, median [IQR] | 15.5 [12] | 16 [11] | 0.65 | |
MES 1, frequency | On first assessment | 54.2% | 760.5% | 0.09 |
On second assessment | 40.3% | 520.9% | 0.34 | |
On both assessments | 30.6% | 470.1% | 0.20 | |
Histological activity, frequency | On first assessment | 38.9% | 520.9% | 0.29 |
On second assessment | 27.8% | 620.5% | <0.05 | |
On both assessments | 15.3% | 430.8% | <0.05 |
IQR, interquartile range; MES, Mayo endoscopy score; SD, standard deviation.
Bolded p-values show statistical significance <0.05.