Table 3.
Variables | HR (95% CI) | p-value |
---|---|---|
Cemented vs. uncemented | 2.5 (1.5–4.2) | 0.001 |
Male | 1.5 (1.2–1.9) | < 0.001 |
Age at surgery (per 1 year) | 1.07 (1.05–1.09) | < 0.001 |
Assisted living | 2.7 (2.2–3.3) | < 0.001 |
Reduced mobility | 1.7 (1.4–2.1) | < 0.001 |
ASA (1–2 vs. 3–4) | 2.1 (1.7–2.7) | < 0.001 |
Regional anesthesia (spinal) | 1.1 (0.8–1.5) | 0.79 |
Medical history | ||
Liver disease | 2.5 (1.1–5.7) | 0.03 |
Renal failure | 2.4 (1.5–3.8) | < 0.001 |
Diabetes | 0.98 (0.69–1.4) | 0.9 |
Stroke | 1.3 (0.96–1.7) | 0.1 |
Peripheral vascular disease | 1.8 (1.0–3.2) | 0.05 |
Arteriosclerosis | 1.0 (0.91–3.2) | 0.1 |
Hypertension | 0.93 (0.74–1.2) | 0.5 |
Angina pectoris | 1.3 (0.92–1.7) | 0.2 |
Previous myocardial infarction | 1.3 (0.94–1.8) | 0.1 |
Congestive heart failure | 1.9 (1.4–2.6) | < 0.001 |
Chronic obstructive pulmonary | ||
disease | 0.95 (0.67–1.4) | 0.8 |
Cancer | 1.7 (1.2–2.4) | 0.002 |
Dementia | 2.3 (1.8–2.8) | < 0.001 |
Arrhythmia | 1.6 (1.2–2.0) | < 0.001 |
Medication | ||
ß-blockers | 1.5 (1.2–1.8) | 0.001 |
Diuretics | 1.7 (1.5–2.2) | < 0.001 |
Antiplatelet drugs | 1.5 (1.2–1.9) | 0.001 |
Nitrates | 1.3 (0.97–1.8) | 0.08 |
Calcium antagonists | 0.92 (0.68–1.2) | 0.6 |
ACE inhibitors | 1.0 (0.78–1.3) | 0.9 |
Insulin | 1.1 (0.68–1.7) | 0.8 |
Warfarin | 0.82 (0.49–1.4) | 0.4 |
Statins | 0.60 (0.40–0.88) | 0.01 |
Preoperative | ||
hemoglobin < 100 g/L | 1.8 (1.1–2.9) | 0.04 |
serum creatinine > 150 µmol/L | 2.3 (1.5–3.5) | < 0.001 |
Grade of hypotension/hypoxia | ||
(2–3 vs. 0–1) | 4.1 (3.0–5.8) | < 0.001 |
Diabetes includes both types I and II. ASA;
ACE = angiotensin converting enzyme.
Unadjusted hazard ratios were calculated for each variable.