Table 2.
Summary statistics for amphotericin B and itraconazole treatment groups following propensity score matching (n = 242).
| Amphotericin B | Itraconazole | SMD | |
|---|---|---|---|
| N | 70 | 70 | – |
| Age (years) | 28.79 (4.71) | 28.66 (6.00) | 0.02 |
| Sex (male) | 54 (77.1) | 56 (80.0) | 0.07 |
| IVDU (yes) | 40 (57.1) | 46 (65.7) | 0.18 |
| History of TB (yes) | 23 (32.9) | 18 (25.7) | 0.16 |
| History of TM (yes) | 5 (7.1) | 5 (7.1) | <0.001 |
| Fever (>38°C) | 26 (37.1) | 24 (34.3) | 0.06 |
| Pulse (beats/min) | 97.63 (16.51) | 97.29 (15.71) | 0.02 |
| SBP (mm/Hg) | 100.14 (11.73) | 98.79 (10.44) | 0.12 |
| Respiratory rate (breaths/minute) | 25.74 (5.10) | 24.74 (4.95) | 0.20 |
| Weight (kg) | 44.61 (7.64) | 42.80 (7.06) | 0.25 |
| Skin lesions (yes) | 31 (44.3) | 49 (70.0) | 0.54 |
| Absolute lymphocyte count (cells/μl) | 0.59 (0.93) | 0.68 (0.86) | 0.10 |
| Hemoglobin (g/dl) | 8.14 (2.40) | 7.90 (2.68) | 0.09 |
| Hematocrit (%) | 25.27 (6.94) | 24.61 (7.75) | 0.09 |
| Platelets (103/μl) | 115.88 (98.84) | 116.01 (97.93) | 0.00 |
| Creatinine (μmol/l) | 106.70 (84.04) | 111.06 (75.33) | 0.06 |
| Sodium (mmol/L) | 129.74 (6.67) | 129.55 (6.26) | 0.03 |
| K (μmol/l) | 4.00 (0.98) | 4.01 (0.86) | 0.01 |
| AST (units/l) | 200.84 (209.80) | 162.71 (180.44) | 0.20 |
| Lower respiratory infection (yes) | 23 (32.9) | 21 (30.0) | 0.06 |
| CNS infection (yes) | 7 (10.0) | 6 (8.6) | 0.05 |
| Fungemia (yes) | 69 (98.6) | 68 (97.1) | 0.10 |
| LOS (days) | 17.29 (11.39) | 15.14 (8.57) | 0.21 |
Note: Summary statistics are presented as count (percentage) of positive value for categorical variables and mean (standard deviation) for continuous variables. SMD: standardized mean difference, n: group sample size, IVDU: intravenous drug use, CNS: central nervous system, AST: aspartate aminotransferase, TB: tuberculosis, TM: Talaromyces marneffei, SBP: systolic blood pressure, K: potassium, LOS: length of stay.