TABLE 5.
Serum ferritin, hemoglobin, hematocrit, and RBC counts at baseline and at 12 and 24 mo1
| n | Baseline | Δ at 12 mo, % | Δ at 24 mo, % | P change2 | P trend2 | P ANCOVA3 | |
|---|---|---|---|---|---|---|---|
| Ferritin, ng/mL | |||||||
| Soy | 38 | 48.3 (37.8, 58.9) | 78.3 (53.2, 103.4) | 128.8 (61.9, 195.6) | <0.001 | <0.001 | 0.608 |
| Placebo | 33 | 60.3 (42.4, 78.3) | 70.2 (45.4, 95.0) | 117.1 (79.9, 157.2) | <0.001 | <0.001 | |
| Hemoglobin, g/dL | |||||||
| Soy | 45 | 14.5 (14.2, 14.8) | 2.7 (1.0, 4.3) | 2.7 (0.8, 4.3) | <0.001 | 0.003 | 0.722 |
| Placebo | 37 | 14.7 (14.3, 15.0) | 1.7 (0.0, 3.5) | 3.3 (1.5, 5.1) | 0.002 | <0.001 | |
| Hematocrit, % | |||||||
| Soy | 46 | 43.6 (42.7, 44.6) | 1.7 (–0.2, 3.6) | 2.6 (0.8, 4.4) | 0.015 | 0.008 | 0.445 |
| Placebo | 37 | 44.1 (43.0, 45.2) | 1.6 (–0.2, 3.5) | 3.6 (1.4, 5.7) | 0.002 | 0.002 | |
| RBCs, 1012/L | |||||||
| Soy | 46 | 5.00 (4.88, 5.08) | –0.9 (–2.2, 0.5) | –0.1 (–1.7, 1.4) | 0.323 | 0.816 | 0.969 |
| Placebo | 38 | 4.99 (4.85, 5.13) | –1.9 (–3.8, 0.0) | 0.2 (–1.9, 2.3) | 0.041 | 0.934 | |
1
Values are means (95% CIs). Only subjects with complete data at baseline, 12 mo, and 24 mo and age, weight, and height at baseline are included in this analysis.
2
One-way repeated-measures ANOVA of change over time.
3
ANCOVA for percentage difference between the 2 treatments at 24 mo, with age, height, and weight at baseline as covariates.