Table 2.
Comparison of QCA and LVG Results Between ACh-Positive and ACh-Negative Groups (n=53)
| ACh-positive (n=36) | ACh-negative (n=17) | P value | |
|---|---|---|---|
| Pre-total QCA area (mm2) | 705.0±135.9 | 731.2±155.4 | NS |
| Post-total QCA area (mm2) | 887.2±166.2** | 864.3±166.9** | NS |
| Change from pre- to post-total QCA area (mm2) | 182.2±84.6 | 133.1±61.1 | <0.05 |
| Pre-total reference length (mm) | 309.3±40.7 | 299.2±37.2 | NS |
| Post-total reference length (mm) | 308.9±40.6 | 298.9±36.7 | NS |
| Change from pre- to post-total reference length (mm) | −0.43±1.9 | −0.27±1.1 | NS |
| Total volume ISDN administered (mL) | 3.8±1.3 | 3.9±1.2 | NS |
| Time from first to second LVG (min) | 48.6±12.1 | 50.5±9.3 | NS |
| Time from final ISDN administration to second LVG (min) |
12.2±5.0 | 12.8±4.5 | NS |
| Pre-LVEDVI (mL/m2) | 66.1±19.5 | 75.9±26.6 | NS |
| Post-LVEDVI (mL/m2) | 55.3±18.4** | 65.6±25.5** | NS |
| Pre-LVESVI (mL/m2) | 30.5±17.3 | 36.1±22.8 | NS |
| Post-LVESVI (mL/m2) | 24.0±17.3** | 30.1±19.8** | NS |
| HR Pre-LVG (/min) | 65.0±10.8 | 67.9±12.8 | NS |
| HR Post-LVG (/min) | 68.6±13.6 | 71.7±14.7 | NS |
| Pre-LVEDP (mmHg) | 17.8±5.6 | 17.1±4.4 | NS |
| Post-LVEDP (mmHg) | 18.6±6.9 | 19.4±8.3 | NS |
| Pre-LVEF (%) | 56.0±12.9 | 55.0±13.3 | NS |
| Post-LVEF (%) | 59.8±15.1** | 56.8±12.4** | NS |
| Post–Pre-LVEF (%) | 3.8±5.7 | 1.9±2.6 | NS |
| Pre-NBP-Sys (mmHg) | 136.8±19.8 | 134.5±19.9 | NS |
| Post-NBP-Sys (mmHg) | 120.7±20.8** | 115.8±12.0** | NS |
Results are expressed as the mean±SD. P values are for comparisons of ACh-positive and -negative groups. Asterisks next to values indicate results of comparisons with pre values (**P<0.01; NS, not significantly different). Total QCA area and total reference length were defined as the area and length, respectively, of the left anterior descending plus left circumflex plus right coronary arteries. ACh, acetylcholine; HR, heart rate; ISDN, isosorbide dinitrate; LVEDP, left ventricular end diastolic pressure; LVEDVI, left ventricular end diastolic volume index; LVEF, left ventricular ejection fraction; LVESVI, left ventricular end systolic volume index; LVG, left ventriculography; NBP, non-invasive blood pressure; QCA, quantitative coronary arteriography; Sys, systolic.