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. 2021 Apr 5;5(2):021503. doi: 10.1063/5.0044027

FIG. 6.

FIG. 6.

Isolation and encapsulation of islets limit mass transfer. Compared to the native pancreas (a), diffusion dramatically reduced for the majority of cells in islets (especially in the core of the cell mass) as a result of loss of blood perfusion following isolation from the acinar tissue (b). Furthermore, microencapsulation increases the distance of islet cells to the surrounding fluid or blood vessels (c). Dark green represents greater mass transport.