Table 1.

Study characteristics

Study	Fluconazole group					Control group
	Number	Weight	Dose	Frequency	Duration	Number	Weight
Kaufman et al. [8] (2001)	50	<1,000 g	3 mg/kg	Every 3 or 2 or 1 days	Weeks 1, 2/3, 4/5, 6	50	<1,000 g
Jannatdoust et al. [22] (2015)	43	<1,250 g	3 mg/kg	Every 3 or 2 or 1 days	Weeks 1, 2/3, 4/5, 6	50	<1,250 g
Aghai et al. [23] (2006)	140	≤1,000 g	3 mg/kg	Every 3 or 2 or 1 days	Weeks 1, 2/3, 4/5, 6	136	≤1,000 g
Healy et al. [12] (2008)	448	<1,000	3 mg/kg	Every 3 or 2 or 1 days	Weeks 1, 2/3, 4/5, 6	206	<1,000 g
Healy et al. [24] (2005)	240	<1,000	3 mg/kg	Every 3 or 2 or 1 days	Weeks 1, 2/3, 4/5, 6	206	<1,000 g
Lee et al. [15] (2016)	264	<1,000 g	3 mg/kg	Twice weekly	4 Weeks	159	<1,000 g
Weitkamp et al. [25] (2008)	42	<750 g	3 mg/kg	Twice weekly	4 Weeks	44	<750 g
Rueda et al. [26] (2010)	252	<1,250	3 mg/kg	Every 2 days	6 Weeks	271	<1,250
Aydemir et al. [27] (2010)	93	<1,500 g	3 mg/kg	Every 3 days	30–45 Days	91	<1,500 g
Manzoni et al. [10] (2007a)	104	<1,500 g	3 mg/kg	Every 3 days/every 2 days	First 2 weeks/weeks 3–6	106	<1,500 g
Manzoni et al. [10] (2007b)	112	<1,500 g	6 mg/kg	Every 3 days/every 2 days	First 2 weeks/weeks 3–6	106	<1,500 g
Bertini et al. [28] (2005)	136	<1,500 g	6 mg/kg	Every 3 days/once daily	First week/weeks 2, 3 ,4	119	< 1500 g
Manzoni et al. [29] (2006)	225	<1,500 g	6 mg/kg	Every 3 days first week then every 2 days	Until 30th–45th day of life	240	<1,500 g
Benjamin et al. [30] (2014)	188	<750 g	6 mg/kg	Twice weekly	6 Weeks	173	<750 g
Parikh et al. [11] (2007)	60	<1,500 g	6 mg/kg	Every 3 days/once daily	First week/weeks 2, 3 ,4	60	<1,500 g
Kicklighter et al. [9] (2001)	53	<1,500 g	6 mg/kg	Every 3 days/every days	Weeks 1/2, 3, 4	50	<1,500 g
Kirpal et al. [31] (2016)	38	<1,500 g	6 mg/kg	Every 2 or 1 days	Weeks 1/2, 3, 4	37	<1,500 g