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. 2021 Apr;26(2):152–157. doi: 10.17712/nsj.2021.2.20200110

Table 2.

- Summary of Peterson’s study results versus the current empirical evidence.

Peterson's study results (percentage of participants' preference of antidepressant treatment) Evidence (APA Guidelines 2000, revised)
Efficacy SSRIs (48%) No difference
Sexual dysfunction Fluoxetine (56%) More common with paroxetine
Agitation Fluoxetine (52%) Comparable to other SSRIs
Discontinuation syndrome Paroxetine (47%) Occurs among short half-life antidepressants
Atypical depression SSRIs (57%) MAOIs
Melancholic depression SSRIs (57%) No specific recommendation, (pharmacotherapy and ECT leads to good responses)

APA - American Psychiatric Association, ECT - electric shock treatment, MAOIs - Monaoamine Oxidase Inhibitors, SSRIs - Selective Serotonin Reuptake Inhibitors