Table 5.
Post-hoc analysis of organ function over time (Days 0, 7, 14 and 35 post ICU admission) in critically-ill COVID-19 patients
| Day post ICU admission | SOFA score over time | P-value | ||
|---|---|---|---|---|
| Total patients (n = 87) | Control group (n = 44) | Intervention (TPE) group (n = 43) | ||
| Baseline (before therapy) | ||||
| Day 0 | 10 (7–13) | 9 (6–12) | 10 (8–13) | 0.07 |
| After therapy | ||||
| Day 7 | 4 (2–7) | 5 (2–8) | 3 (2–4) | 0.0001* |
| Day 14 | 2 (0–2) | 3 (2–4) | 1 (0.5–1.5) | 0.03* |
| Day 35 | 1 (0.5–1.5) | 1 (0.5–1.5) | 0.5 (0–1) | 0.07 |
ICU, intensive care unit; SOFA, Sequential Organ Function Assessment; TPE, therapeutic plasma exchange.
⁎
P ≤ 0.05 (with Bonferroni correction) was considered statistically significant.