Table 3.
Depressive symptoms, anxiety, and quality of life among participants, stratified by number of oocyte retrievals, number of children, and age categories (n = 513).
| Number of oocyte retrievals | Number of children | Age categories | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | 1 | 2 | 3 ≥ | p value | 0 | 1 ≥ | p value | < 30.0 | 30.0–34.9 | 35.0–39.9 | ≥ 40.0 | p value | |||||||||||
| Mean or N | (SD) or % | Mean or N | (SD) or % | Mean or N | (SD) or % | Mean or N | (SD) or % | Mean or N | (SD) or % | Mean or N | (SD) or % | Mean or N | (SD) or % | Mean or N | (SD) or % | Mean or N | (SD) or % | Mean or N | (SD) or % | ||||
| Depression symptoms (QIDS)a | 6.3 | (4.7) | 7.3 | (4.7) | 6.9 | (4.7) | 8.4 | (4.9) | 7.2 | (4.8) | 5.5 | (4.2) | 8.3 | (4.3) | 7.2 | (5.1) | 6.7 | (4.7) | 6.2 | (4.1) | |||
| None | 72 | 56% | 109 | 42% | 44 | 46% | 9 | 32% | 0.31 | 196 | 43% | 38 | 64% | 0.05 | 13 | 22% | 83 | 47% | 101 | 49% | 37 | 54% | < 0.01 |
| Mild | 30 | 23% | 88 | 34% | 35 | 37% | 10 | 36% | 151 | 33% | 12 | 20% | 30 | 51% | 49 | 28% | 63 | 30% | 21 | 30% | |||
| Moderate | 21 | 16% | 47 | 18% | 10 | 11% | 7 | 25% | 78 | 17% | 7 | 12% | 10 | 17% | 30 | 17% | 36 | 17% | 9 | 13% | |||
| Severe | 5 | 4% | 15 | 6% | 5 | 5% | 2 | 7% | 25 | 6% | 2 | 3% | 6 | 10% | 14 | 8% | 5 | 2% | 2 | 3% | |||
| Very severe | 1 | 1% | 2 | 1% | 1 | 1% | 0 | 0% | 4 | 1% | 0 | 0% | 0 | 0% | 1 | 1% | 3 | 1% | 0 | 0% | |||
| Anxiety (STAI) | |||||||||||||||||||||||
| Statea | 51.5 | (12) | 51.8 | (11.2) | 51.4 | (11.3) | 53.2 | (8.3) | 52.1 | (11.3) | 48.8 | (10.8) | 54.9 | (10) | 52.8 | (11.7) | 50.9 | (11.1) | 48.7 | (10.7) | |||
| Category 1 | 12 | 9% | 15 | 6% | 7 | 7% | 0 | 0% | 0.73 | 28 | 6% | 6 | 10% | 0.36 | 1 | 2% | 10 | 6% | 14 | 7% | 9 | 13% | 0.08 |
| Category 2 | 17 | 13% | 47 | 18% | 19 | 20% | 4 | 14% | 75 | 17% | 12 | 20% | 8 | 14% | 27 | 15% | 42 | 20% | 10 | 14% | |||
| Category 3 | 50 | 39% | 92 | 35% | 34 | 36% | 13 | 46% | 165 | 36% | 24 | 41% | 19 | 32% | 62 | 35% | 75 | 36% | 33 | 48% | |||
| Category 4 (high anxiety) | 37 | 29% | 83 | 32% | 24 | 25% | 7 | 25% | 137 | 30% | 14 | 24% | 23 | 39% | 58 | 33% | 58 | 28% | 12 | 17% | |||
| Category 5 (high anxiety) | 13 | 10% | 24 | 9% | 11 | 12% | 4 | 14% | 49 | 11% | 3 | 5% | 8 | 14% | 20 | 11% | 19 | 9% | 5 | 7% | |||
| Traita | 52.0 | (12) | 53.4 | (11.3) | 51.3 | (11.5) | 54.9 | (9.3) | 53.1 | (11.4) | 49.9 | (11.3) | 57.1 | (10.8) | 53.7 | (11.7) | 51.9 | (10.8) | 49.0 | (11.7) | |||
| Category 1 | 7 | 5% | 13 | 5% | 4 | 4% | 0 | 0% | 0.31 | 20 | 4% | 4 | 7% | 0.18 | 2 | 3% | 8 | 5% | 9 | 4% | 5 | 7% | 0.06 |
| Category 2 | 11 | 9% | 12 | 5% | 8 | 8% | 3 | 11% | 29 | 6% | 5 | 8% | 1 | 2% | 8 | 5% | 17 | 8% | 8 | 12% | |||
| Category 3 | 32 | 25% | 66 | 25% | 28 | 29% | 2 | 7% | 107 | 24% | 21 | 36% | 13 | 22% | 40 | 23% | 57 | 27% | 18 | 26% | |||
| Category 4 (high anxiety) | 55 | 43% | 119 | 46% | 38 | 40% | 19 | 68% | 210 | 46% | 21 | 36% | 25 | 42% | 82 | 46% | 91 | 44% | 33 | 48% | |||
| Category 5 (high anxiety) | 24 | 19% | 51 | 20% | 17 | 18% | 4 | 14% | 88 | 19% | 8 | 14% | 18 | 31% | 39 | 22% | 34 | 16% | 5 | 7% | |||
| Quality of life (SF-12) | |||||||||||||||||||||||
| Physical functioninga | 51.3 | (8.8) | 50.7 | (9.4) | 50.3 | (9.8) | 49.6 | (11.7) | 0.29 | 50.7 | (9.6) | 50.8 | (8.1) | 0.96 | 51.0 | (9.1) | 50.3 | (10) | 51.2 | (9) | 50.4 | (9.7) | 0.88 |
| Role (physical)a | 46.1 | (10.7) | 42.3 | (11.9) | 43.9 | (12.4) | 40.7 | (11.4) | 0.03 | 43.2 | (11.8) | 45.6 | (11.6) | 0.14 | 41.0 | (12.2) | 43.4 | (12.1) | 44.0 | (11.4) | 44.4 | (11.7) | 0.10 |
| Bodily paina | 46.7 | (11) | 43.7 | (12.2) | 45.5 | (11.4) | 43.8 | (10.2) | 0.27 | 44.3 | (11.8) | 48.1 | (10.8) | 0.02 | 42.0 | (12.2) | 43.8 | (11.8) | 46.2 | (11.4) | 45.0 | (11.2) | 0.03 |
| General healtha | 53.8 | (9) | 53.3 | (9) | 54.1 | (9.8) | 51.5 | (12.3) | 0.58 | 53.3 | (9.5) | 54.8 | (7.9) | 0.23 | 53.5 | (9.7) | 53.0 | (10.1) | 53.7 | (9) | 54.0 | (8.3) | 0.56 |
| Vitalitya | 47.8 | (8.9) | 46.3 | (9.1) | 48.0 | (8.9) | 47.2 | (9.1) | 0.94 | 46.8 | (8.9) | 48.8 | (9.6) | 0.11 | 45.5 | (9.2) | 46.3 | (9.2) | 47.8 | (9) | 48.0 | (8.4) | 0.04 |
| Social functioninga | 42.9 | (13.4) | 41.3 | (14.7) | 42.0 | (14.4) | 39.0 | (15.1) | 0.29 | 41.3 | (14.4) | 44.4 | (13.8) | 0.13 | 37.6 | (14.8) | 40.3 | (14.5) | 43.0 | (14) | 45.0 | (13.7) | < 0.01 |
| Role (emotional)a | 41.8 | (11.5) | 39.5 | (12.4) | 41.7 | (11.1) | 37.2 | (13.2) | 0.29 | 39.7 | (11.9) | 45.9 | (11.1) | < 0.01 | 37.4 | (12.3) | 39.6 | (11.8) | 41.4 | (11.9) | 41.8 | (12.3) | 0.02 |
| Mental healtha | 43.6 | (11.7) | 42.1 | (10.5) | 43.2 | (10.3) | 41.1 | (11.8) | 0.42 | 42.3 | (10.6) | 44.9 | (10.3) | 0.09 | 38.3 | (10) | 41.7 | (10.1) | 43.7 | (10.7) | 45.4 | (10.8) | < 0.01 |
To calculate p values, we used Chi-square testing for QIDS and STAI (state and trait) and simple linear regression for subscales of SF-12 treating categories as ordinal.
aMean and standard deviations.