Table 2.
Plasma bilirubin with regard to medication and tobacco use in individuals with FEP.
| Medication/tobacco | Median [Interquartile range] (n) | ||
|---|---|---|---|
| Plasma bilirubin levels (µmol/l) | p valuea | ||
| FEP patients on drug or on tobacco | FEP patients off drug or off tobacco | ||
| Antipsychoticsb | 10.0 [10.0–13.0] (16) | 11.0 [8.0–12.0] (23) | 0.70 |
| Antidepressantsc | 12.5 [10.0–16.5] (4) | 10.0 [9.0–12.0] (35) | 0.31 |
| Antiepilepticsd | 8.0 (1) | 11.0 [9.0–13.0] (38) | 0.25 |
| Benzodiazepinese | 12.0 [9.0–16.0] (11) | 10.5 [9.0–12.0] (28) | 0.46 |
| Zopiclone | 11.0 [10.0–13.0] (10) | 10.0 [9.0–12.0] (29) | 0.18 |
| Phenothiazine derivatesf | 10.0 [10.0–13.0] (11) | 11.0 [9.0–12.5] (28) | 0.73 |
| Any treatmentsg | 11.0 [9.0–13.0] (27) | 10.5 [7.0–14.0] (12) | 0.62 |
| Tobacco | 10.0 [9.5–11.5] (12) | 11.0 [8.5–12.5] (24) | 0.74 |
Abbreviations: FEP, First-episode psychosis; (n), number. aMann-Whitney U-test, two-sided. bAll antipsychotics combined. cAll antidepressants combined. dAll antiepileptic’s combined. eAll benzodiazepines combined. fAll Phenothiazine derivatives combined. gEither N, AD, AE, BZD, Z, PD or a combination of these drugs.