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. 2021 Apr 6;11:7517. doi: 10.1038/s41598-021-87086-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The miRNA-gene network for miRNAs associated with genes related to idiopathic DCM^SEV. (A) Venn diagram showing overlap of gene targets of miR-130b-3p, miR-150-5p and miR-210-3p. (B) GO and KEGG analysis of miR-130b-3p, miR-150-5p and miR-210-3p target genes; the x-axis indicates KEGG pathway categories and the y-axis indicates the target numbers of genes. (C) miRNA-gene network for miR-210-3p. The network was built using 83 targeted genes and predicted interactions from the miRDB database. (D) PPI analysis performed using the STRING database for the target genes of miR-210-3p. The disconnected nodules are hidden. Bold lines indicate stronger association. Abbreviations: DCM^SEV, dilated cardiomyopathy with ejection fraction ≤ 30%.