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. 2021 Apr 6;11:7517. doi: 10.1038/s41598-021-87086-1

Table 4.

Correlation between the echocardiographic parameter and individual microRNAs for LVEF categorization in idiopathic DCM.

microRNA LVEF (%) LVESD (mm) Left atrial dimension (mm)
DCMSEV DCMMOD DCMSEV DCMMOD DCMSEV DCMMOD
Pearson r p Pearson r p Pearson r p Pearson r p Pearson r p Pearson r p
Let-7a-5p − 0.677 0.006 0.140 0.388 − 0.103 0.726 − 0.489 0.002 0.277 0.318 − 0.362 0.022
Let-7 g-5p − 0.609 0.016 0.181 0.269 − 0.286 0.321 − 0.408 0.011 0.368 0.269 − 0.532  < 0.001
miR-1-3p − 0.190 0.498 0.204 0.206 0.046 0.875 − 0.218 0.183 0.242 0.385 − 0.433 0.005
miR-16-5p − 0.190 0.498 0.204 0.206 0.046 0.875 − 0.218 0.183 0.242 0.385 − 0.433 0.005
miR-16–2-3p − 0.438 0.102 0.130 0.424 0.044 0.882 − 0.559  < 0.001 0.219 0.432 − 0.262 0.102
miR-19b-3p − 0.527 0.043 0.193 0.233 0.111 0.705 − 0.444 0.005 0.276 0.319 − 0.306 0.054
miR-25-3p − 0.538 0.039 0.106 0.515 0.077 0.795 − 0.544  < 0.001 0.155 0.580 − 0.246 0.127
miR-29a-3p − 0.641 0.010 0.168 0.300 0.180 0.538 − 0.261 0.109 0.337 0.219 − 0.336 0.034
miR-30b-5p − 0.603 0.017 0.179 0.269 − 0.312 0.278 − 0.376 0.018 0.313 0.256 − 0.436 0.005
miR-30e-3p − 0.629 0.012 0.234 0.145 − 0.130 0.658 − 0.335 0.037 0.385 0.157 − 0.347 0.028
miR-130b-3p − 0.394 0.146 0.094 0.564 0.109 0.710 − 0.296 0.067 0.554 0.032 − 0.269 0.093
miR-133a-3p − 0.455 0.088 0.092 0.574 0.160 0.584 − 0.359 0.025 0.208 0.456 − 0.348 0.028
miR-133b − 0.361 0.186 0.179 0.268 0.028 0.924 − 0.194 0.236 0.140 0.619 − 0.444 0.004
miR-142-3p − 0.569 0.027 0.210 0.193 − 0.080 0.787 − 0.417 0.008 0.359 0.189 − 0.349 0.027
miR-145-5p − 0.614 0.015 0.130 0.423 0.109 0.711 − 0.425 0.007 0.324 0.239 − 0.382 0.015
miR-150-5p − 0.540 0.038 0.178 0.272 − 0.148 0.614 − 0.357 0.025 0.327 0.234 − 0.419 0.007
miR-192-5p − 0.464 0.082 0.237 0.141 0.152 0.603 − 0.536  < 0.001 0.191 0.495 − 0.252 0.117
miR-199a-3p − 0.692 0.004 0.184 0.257 0.065 0.826 − 0.198 0.228 0.396 0.144 − 0.401 0.010
miR-210-3p − 0.555 0.032 0.188 0.244 0.056 0.848 − 0.405 0.011 0.285 0.304 − 0.287 0.073
miR-215-3p − 0.425 0.114 0.201 0.213 − 0.003 0.993 − 0.583 0.000 0.109 0.699 − 0.301 0.059
miR-324-3p − 0.667 0.007 0.183 0.257 − 0.053 0.857 − 0.448 0.004 0.270 0.330 − 0.293 0.066
miR-363-3p − 0.463 0.082 0.075 0.644 0.070 0.811 − 0.582  < 0.001 0.125 0.657 − 0.189 0.244
miR-454-3p − 0.692 0.004 0.085 0.603 − 0.290 0.315 − 0.293 0.070 0.250 0.368 − 0.416 0.008
miR-532-5p − 0.480 0.070 0.283 0.077 − 0.058 0.844 − 0.487 0.002 0.217 0.438 − 0.308 0.053
miR-629-5p − 0.383 0.159 − 0.057 0.729 0.017 0.954 − 0.419 0.008 0.151 0.592 − 0.057 0.728
miR-660-5p − 0.500 0.058 0.102 0.530 0.313 0.276 − 0.538  < 0.001 0.231 0.407 − 0.118 0.467

Abbreviations: DCMMOD, dilated cardiomyopathy with ejection fraction ≥ 31–49%; DCMSEV, dilated cardiomyopathy with ejection fraction ≤ 30%; LVEF, left ventricle ejection fraction; LVESD, left ventricle end-systolic diameter. Coefficient significant at p < 0.05.