Table 2.
Comparison of FA, AD, RD, and MD in bipolar disorder type-II, unipolar depression, and healthy controls.
| Cluster | Measure | F | p-uncor F-test |
q F-test |
df | t | p-uncor t-test |
q t-test |
Summary |
|---|---|---|---|---|---|---|---|---|---|
|
Cluster 1 N = 14 vicinity of af_l |
FA | 13.69 | 0.000013 | 0.000169 | 59 | − 4.307 | 0.000063 | 0.000349 | BD < HC |
| − 0.939 | 0.351637 | 0.40994 | HC = UD | ||||||
| − 5.081 | 0.000004 | 0.000072 | BD < UD | ||||||
| MD | 8.82 | 0.000446 | 0.001933 | 59 | 3.276 | 0.001766 | 0.004102 | BD > HC | |
| 0.602 | 0.54927 | 0.58158 | HC = UD | ||||||
| 3.759 | 0.000394 | 0.001182 | BD > UD | ||||||
| RD | 12 | 0.000042 | 0.000437 | 59 | 4.03 | 0.000162 | 0.000648 | BD > HC | |
| 0.572 | 0.569691 | 0.59446 | HC = UD | ||||||
| 4.465 | 0.000037 | 0.000266 | BD > UD | ||||||
|
Cluster 2 N = 18 atr_r, cbd_r, fmi |
FA | 7.3 | 0.001465 | 0.004761 | 59 | − 3.964 | 0.000202 | 0.000727 | BD < HC |
| 2.03 | 0.046919 | 0.071876 | HC = UD | ||||||
| − 1.95 | 0.0559 | 0.082407 | BD = UD | ||||||
| RD | 6.82 | 0.002167 | 0.006549 | 59 | 3.784 | 0.000363 | 0.001136 | BD > HC | |
| − 2.094 | 0.040545 | 0.066346 | HC = UD | ||||||
| 1.714 | 0.091718 | 0.124598 | BD = UD | ||||||
|
Cluster 3 N = 26 af_l, str_l |
FA | 4.4 | 0.016496 | 0.037295 | 59 | − 2.602 | 0.011703 | 0.021606 | BD < HC |
| 2.806 | 0.006783 | 0.012852 | HC > UD | ||||||
| 0.108 | 0.914594 | 0.914594 | BD = UD | ||||||
|
Cluster 4 N = 36 af_l, cst_l, str_l |
FA | 6.76 | 0.002267 | 0.006549 | 59 | − 3.887 | 0.00026 | 0.000891 | BD < HC |
| 1.809 | 0.075481 | 0.104512 | HC = UD | ||||||
| − 2.083 | 0.041615 | 0.066584 | BD = UD | ||||||
| RD | 4.15 | 0.020599 | 0.044631 | 59 | 3.015 | 0.003787 | 0.00802 | BD > HC | |
| − 2.036 | 0.046282 | 0.071876 | HC = UD | ||||||
| 1.02 | 0.311811 | 0.375493 | BD = UD | ||||||
|
Cluster 5 N = 62 af_l, ifo_l, mdlf_l |
FA | 9.8 | 0.000211 | 0.001372 | 59 | − 4.128 | 0.000117 | 0.000526 | BD < HC |
| 3.326 | 0.001519 | 0.003646 | HC > UD | ||||||
| − 0.889 | 0.377415 | 0.426012 | BD = UD | ||||||
|
Cluster 6 N = 90 vicinity of cbd_l |
FA | 11.07 | 0.000083 | 0.000654 | 59 | − 3.422 | 0.001135 | 0.002818 | BD < HC |
| 4.534 | 0.000029 | 0.000248 | HC > UD | ||||||
| 0.936 | 0.353004 | 0.40994 | BD = UD | ||||||
| RD | 6.47 | 0.002887 | 0.007901 | 59 | 2.106 | 0.039448 | 0.066052 | BD = HC | |
| − 3.725 | 0.000439 | 0.001232 | HC < UD | ||||||
| − 1.456 | 0.150623 | 0.200831 | BD = UD | ||||||
|
Cluster 7 N = 115 af_l, mdlf_l |
FA | 10.99 | 0.000088 | 0.000654 | 59 | − 2.829 | 0.006364 | 0.012384 | BD < HC |
| 4.952 | 0.000006 | 0.000086 | HC > UD | ||||||
| 1.907 | 0.061395 | 0.086675 | BD = UD | ||||||
| RD | 4.8 | 0.011736 | 0.02774 | 59 | 1.397 | 0.167509 | 0.219285 | BD = HC | |
| − 3.505 | 0.000878 | 0.002258 | HC < UD | ||||||
| − 1.939 | 0.057227 | 0.082407 | BD = UD | ||||||
|
Cluster 8 N = 214 af_l, ifo_l, ilf_l, mdlf_l, or_l |
FA | 9.28 | 0.000313 | 0.001628 | 59 | − 4.273 | 0.000071 | 0.000365 | BD < HC |
| 3.721 | 0.000445 | 0.001232 | HC > UD | ||||||
| − 0.659 | 0.512459 | 0.550702 | BD = UD | ||||||
|
Cluster 9 N = 270 af_r, fa_r |
FA | 8.44 | 0.000596 | 0.002201 | 59 | − 3.036 | 0.003565 | 0.007778 | BD < HC |
| 4.054 | 0.000149 | 0.000631 | HC > UD | ||||||
| 0.86 | 0.393062 | 0.435392 | BD = UD | ||||||
| RD | 4.94 | 0.010376 | 0.025693 | 59 | 2.167 | 0.034251 | 0.058716 | BD = HC | |
| − 3.184 | 0.002319 | 0.005218 | HC < UD | ||||||
| − 0.887 | 0.378677 | 0.426012 | BD = UD | ||||||
|
Cluster 10 N = 428 af_r, fmi, ifo_r, uf_r |
FA | 8.47 | 0.000583 | 0.002201 | 59 | − 2.172 | 0.033883 | 0.058716 | BD = HC |
| 4.314 | 0.000062 | 0.000349 | HC > UD | ||||||
| 1.946 | 0.056395 | 0.082407 | BD = UD | ||||||
| RD | 5.94 | 0.004473 | 0.01163 | 59 | 1.174 | 0.245021 | 0.3095 | BD = HC | |
| − 3.837 | 0.000306 | 0.001001 | HC < UD | ||||||
| − 2.469 | 0.016459 | 0.029626 | BD < UD | ||||||
|
Cluster 11 N = 1013 af_l, atr_l, fa_l, fmi, ifo_l, str_l, uf_l |
FA | 15.8 | 0.000003 | 0.000078 | 59 | − 5.409 | 0.000001 | 0.000036 | BD < HC |
| 4.515 | 0.000031 | 0.000248 | HC > UD | ||||||
| − 1.018 | 0.312911 | 0.375493 | BD = UD | ||||||
| RD | 9.51 | 0.000263 | 0.00152 | 59 | 3.603 | 0.000646 | 0.001723 | BD > HC | |
| − 3.981 | 0.000191 | 0.000724 | HC < UD | ||||||
| − 0.238 | 0.812573 | 0.824018 | BD = UD | ||||||
|
Cluster 12 N = 1945 af_l, af_r, cbd_r, fma, mdlf_l, mdlf_r, or_r |
FA | 15.05 | 0.000005 | 0.000087 | 59 | − 5.15 | 0.000003 | 0.000072 | BD < HC |
| 4.807 | 0.000011 | 0.000113 | HC > UD | ||||||
| − 0.491 | 0.624988 | 0.642845 | BD = UD | ||||||
| RD | 8.36 | 0.000635 | 0.002201 | 59 | 2.97 | 0.004307 | 0.00886 | BD > HC | |
| − 4.164 | 0.000103 | 0.000494 | HC < UD | ||||||
| − 1.028 | 0.30799 | 0.375493 | BD = UD | ||||||
|
Cluster 13 N = 5752 af_l, af_r, atr_l, atr_r, cbd_l, cbd_r, cst_r, fa_r, fmi, ifo_r, slf3_r, str_l, str_r |
FA | 17.87 | 0.000001 | 0.000052 | 59 | − 4.8 | 0.000011 | 0.000113 | BD < HC |
| 5.793 | < 0.00001 | < 0.00001 | HC > UD | ||||||
| 0.778 | 0.439516 | 0.479472 | BD = UD | ||||||
| RD | 9 | 0.000388 | 0.001834 | 59 | 2.903 | 0.005198 | 0.010396 | BD > HC | |
| − 4.381 | 0.000049 | 0.000321 | HC < UD | ||||||
| − 1.298 | 0.199224 | 0.256145 | BD = UD |
Values in bold correspond to the entries which passed FDR q < 0.05 threshold.