Table 4.
Multivariable logistic regression model for donor and recipient factors independently associated with recipient one-year survival
| 95% Confidence Interval | ||||
|---|---|---|---|---|
| Predictor | Odds Ratio | Lower | Upper | p-value |
| Donor/graft characteristics | ||||
| Age (per 5 years) | 1.00 | 0.96 | 1.03 | 0.817 |
| Male sex (vs female) | 1.14 | 0.93 | 1.38 | 0.207 |
| Race/ethnicity (reference: white) | ||||
| Black | 0.67 | 0.55 | 0.82 | <0.001 |
| Hispanic | 0.80 | 0.64 | 1.00 | 0.054 |
| Other | 1.16 | 0.73 | 1.83 | 0.541 |
| BMI (per unit) | 1.01 | 0.99 | 1.03 | 0.267 |
| Cigarette use | 0.75 | 0.61 | 0.93 | 0.009 |
| Diabetes | 0.65 | 0.48 | 0.90 | 0.008 |
| Donor cause of death (reference: head trauma) | ||||
| Anoxia | 1.01 | 0.77 | 1.34 | 0.922 |
| Cerebrovascular/stroke | 0.94 | 0.76 | 1.17 | 0.592 |
| CNS tumor | 0.87 | 0.37 | 2.05 | 0.750 |
| Other | 0.92 | 0.55 | 1.54 | 0.743 |
| Ischemic time | ||||
| <5 hours (per hour) | 1.03 | 0.92 | 1.15 | 0.592 |
| ≥5 hours (per hour) | 0.88 | 0.81 | 0.95 | 0.001 |
| P/F ratio (per 10 units) | 0.99 | 0.99 | 1.00 | 0.019 |
| Recipient characteristics | ||||
| Male sex (vs female) | 0.87 | 0.72 | 1.05 | 0.139 |
| Lung allocation score (LAS, per 5 units) | 0.94 | 0.91 | 0.96 | <0.001 |
| Donor-Recipient pTLC ratio | ||||
| <1 (per 0.1 unit increase) | 1.04 | 0.94 | 1.14 | 0.450 |
| ≥1 | 1.00 | 0.93 | 1.06 | 0.903 |
| Race/ethnicity (reference: white) | ||||
| Black | 1.05 | 0.78 | 1.39 | 0.765 |
| Hispanic | 1.09 | 0.76 | 1.57 | 0.641 |
| Other | 0.85 | 0.50 | 1.46 | 0.559 |
| Total bilirubin | ||||
| <0.75 mg/dL (per mg/dL) | 0.59 | 0.39 | 0.90 | 0.015 |
| ≥0.75 mg/dL (per mg/dL) | 0.96 | 0.87 | 1.06 | 0.400 |
| ECMO at transplant | 0.26 | 0.13 | 0.53 | <0.001 |
| Center annual lung transplant volume | ||||
| <40 (per 5 transplants) | 1.09 | 1.03 | 1.15 | 0.007 |
| ≥40 (per 5 transplants) | 0.97 | 0.90 | 1.04 | 0.367 |
| Single lung transplant | 0.82 | 0.68 | 1.00 | 0.045 |
CNS, central nervous system; P/F, PaO2/FiO2; BMI, body mass index; ECMO, extracorporeal membrane oxygenation