Table 5.
Multivariable logistic regression model for donor and recipient factors independently associated with recipient ten-year survival among recipients who survived at least one year
| 95% Confidence Interval | ||||
|---|---|---|---|---|
| Predictor | Odds Ratio | Lower | Upper | p-value |
| Donor/graft characteristics | ||||
| Age (per 5 years) | 0.96 | 0.93 | 1.00 | 0.019 |
| Male sex (vs female) | 1.13 | 0.94 | 1.35 | 0.189 |
| Race/ethnicity (reference: white) | ||||
| Black | 0.90 | 0.74 | 1.09 | 0.285 |
| Hispanic | 0.98 | 0.79 | 1.21 | 0.836 |
| Other | 0.95 | 0.65 | 1.39 | 0.796 |
| BMI (per unit) | 1.00 | 0.99 | 1.02 | 0.622 |
| Cigarette use | 0.88 | 0.72 | 1.09 | 0.251 |
| Diabetes | 0.85 | 0.61 | 1.19 | 0.346 |
| Donor cause of death (reference: head trauma) | ||||
| Anoxia | 1.08 | 0.84 | 1.38 | 0.557 |
| Cerebrovascular/stroke | 1.13 | 0.93 | 1.37 | 0.237 |
| CNS tumor | 1.00 | 0.46 | 2.18 | 0.998 |
| Other | 1.29 | 0.80 | 2.08 | 0.298 |
| Ischemic time | ||||
| <5 hours (per hour) | 1.11 | 1.00 | 1.24 | 0.053 |
| ≥5 hours (per hour) | 0.98 | 0.91 | 1.06 | 0.563 |
| P/F ratio | ||||
| <450 (per 10 units) | 1.01 | 1.00 | 1.02 | 0.105 |
| ≥450 (per 10 units) | 0.99 | 0.98 | 1.00 | 0.207 |
| Recipient characteristics | ||||
| Male sex (vs female) | 0.87 | 0.74 | 1.03 | 0.108 |
| Lung allocation score (LAS, per 5 units) | 0.99 | 0.96 | 1.02 | 0.351 |
| Donor-Recipient pTLC ratio | ||||
| <1 (per 0.1 unit increase) | 1.02 | 0.93 | 1.12 | 0.617 |
| ≥1 | 0.99 | 0.93 | 1.05 | 0.669 |
| Race/ethnicity (reference: white) | ||||
| Black | 1.00 | 0.78 | 1.30 | 0.980 |
| Hispanic | 1.14 | 0.82 | 1.59 | 0.446 |
| Other | 0.90 | 0.52 | 1.56 | 0.713 |
| Total bilirubin (per mg/dL) | 1.02 | 0.94 | 1.12 | 0.610 |
| ECMO at transplant | 1.23 | 0.43 | 3.54 | 0.704 |
| Center annual lung transplant volume | ||||
| <40 (per 5 transplants) | 1.04 | 1.00 | 1.09 | 0.087 |
| ≥40 (per 5 transplants) | 1.00 | 0.95 | 1.04 | 0.855 |
| Single lung transplant | 0.50 | 0.42 | 0.60 | <0.001 |
CNS, central nervous system; P/F, PaO2/FiO2; BMI, body mass index; ECMO, extracorporeal membrane oxygenation