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. 2021 Mar 24;12:627897. doi: 10.3389/fmicb.2021.627897

TABLE 2.

Changes of bacterial quantity and the rates of mutant resistant to CHL and phages after 48 h incubation with AB91118 under different treatments.

Treatment Bacterial quantity after 48 h incubation Mutant rates
Resistant to CHL (1 MIC) Resistant to LQ7 (MOI 1000) Resistant to ELQ7P-20 (MOI 1000)
CHL (1/2 MIC) 2.70 ± 0.99 × 109 0.55 ± 0.03 4.50 ± 0.71 × 10–5 8.50 ± 0.71 × 10–5
LQ7 (MOI 1) 1.45 ± 0.21 × 109 0.40 ± 0.11 6.10 ± 1.55 × 10–4 2.80 ± 1.41 × 10–4
ELQ7P-20 (MOI 1) 1.65 ± 1.52 × 108 0.12 ± 0.07 8.70 ± 0.42 × 10–3 6.65 ± 0.35 × 10–3
CHL + LQ7 1.30 ± 0.42 × 106 0.93 ± 0.01 2.25 ± 0.35 × 10–2 2.92 ± 1.29 × 10–3
CHL + ELQ7P-20 4.05 ± 1.70 × 105 0.03 ± 0.01 5.96 ± 0.21 × 10–3 1.37 ± 0.11 × 10–3
LQ7 + ELQ7P-20 5.65 ± 1.62 × 108 0.02 ± 0.01 8.50 ± 0.71 × 10–2 3.60 ± 0.57 × 10–2
CHL + LQ7 + ELQ7P-20 3.10 ± 1.27 × 106 0.07 ± 0.01 3.75 ± 0.35 × 10–3 7.72 ± 0.71 × 10–4
Control 4.00 ± 0.01 × 109 0 3.00 ± 1.41 × 10–5 7.00 ± 1.41 × 10–5