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. 2021 Mar 24;12:644012. doi: 10.3389/fmicb.2021.644012

TABLE 3.

The average, SD, and maximum MCC values of 11 OTU picking methods on the simulated dataset.

DMSC (0.04) USEARCH (0.01) DySC (0.03) ESPRIT-Forest (0.04) CD-HIT (0.03) CROP (0.03)
Max. MCC 0.9980 0.9369 0.9838 0.9947 0.9840 0.9980
OTUs number 9 528 17 16 27 9
Ave. MCC 0.9363 0.8198 0.7929 0.9286 0.9120 0.8347
SD of MCC 0.0343 0.0737 0.1750 0.0366 0.0451 0.1585

VSEARCH (0.01) DNACLUST (0.04) Swarm (d = 15) GramClust (0.05) DBH (0.03) Mothur-AL (0.04)

Max. MCC 0.9349 0.9921 0.9868 0.9106 0.9868 0.9980
OTUs number 1,291 15 9 9 9 9
Ave. MCC 0.8204 0.8891 0.5474 0.7832 0.8879 0.9564
SD of MCC 0.0578 0.0567 0.1385 0.1436 0.0781 0.0270

The value in the parentheses is the clustering threshold where each method achieves its peak MCC. For the Swarm method, it is the value of parameter d.