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ADR 10 most frequent types among fatal cases, n = 274 a .
| Adverse reaction type | n (%) |
|---|---|
| Hemorrhage | 209 (76) |
| Renal failure | 21 (8) |
| Cardiac arrest | 20 (7) |
| Pharmacokinetic interaction b | 12 (4) |
| Hematologic disorder | 10 (4) |
| Central nervous system depression | 9 (3) |
| Arrhythmia | 7 (3) |
| Nonhemorrhagic shock | 7 (3) |
| Digestive system disorder | 6 (2) |
| Hyperkaliemia | 5 (2) |
Some cases contained ADRs belonging to different types.
Increase or decrease in plasma concentration.
