Table 1.

Basic characteristics of TCGA CM patients.

Characteristics	Groups	Total (N=459)		Training cohort (N=229)		Validation cohort (N=230)
		No	%	No	%	No	%
Age	≤58	233	50.7	116	50.7	117	50.9
	>58	226	49.3	113	49.3	113	49.1
Sex	Female	175	38.1	82	35.8	93	40.4
	Male	284	61.9	147	64.2	137	59.6
Metastasis	No	410	89.3	209	91.3	201	87.4
	Yes	23	5	9	3.9	14	6.1
	missing	26	5.7	11	4.8	15	6.5
Ulceration	No	145	31.6	70	30.6	75	32.6
	Yes	165	35.9	92	40.2	73	31.7
	Missing	149	32.5	67	29.2	82	35.7
Pathologic Stage	0	6	1.3	3	1.3	3	1.3
	I	77	16.8	40	17.5	37	16.1
	II	139	30.3	73	31.8	66	28.7
	III	169	36.8	81	35.4	88	38.3
	IV	22	4.8	9	4	13	5.6
	Missing	46	10	23	10	23	10
Tumor Site	Trunk	166	36.2	86	37.6	80	34.8
	Extremities	194	42.3	100	43.7	94	40.9
	Head and neck	35	7.6	15	6.5	20	8.7
	Missing	64	13.9	28	12.2	36	15.6
Breslow thickness (mm)	≤2	136	29.6	73	31.9	63	27.4
	2–5	113	24.6	52	22.7	61	26.5
	>5	105	22.9	59	25.8	46	20
	Missing	105	22.9	45	19.6	60	26.1
Chemotherapy	No	323	70.4	153	66.8	170	73.9
	Yes	88	19.2	49	21.4	39	17
	Missing	48	10.4	27	11.8	21	9.1
Radiotherapy	No	341	74.3	170	74.2	171	74.3
	Yes	73	15.9	34	14.9	39	17
	Missing	45	9.8	25	10.9	20	8.7