Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Comparison between the characteristics of cancer-derived Ig and B cell-derived Ig.
| Cancer-derived Ig | B cell-derived Ig | |
|---|---|---|
| Expression profile | Cancer cell | B cell |
| Function | Promotes tumorigenesis Promotes tumor immune escape Induces inflammation Activates platelet aggregation |
Antibody activity B cell development |
| Recombination patterns of variable region | Restricted | Highly variable |
| N-Glycosylation site | Asn162 | Asn297 |
| Transcription factor | Oct-1 | Oct-2 |
