TABLE 4.
The 3D positioning of different forms tested benzimidazole drugs inside the deep binding pocket of NZO within Tubulin subunit B and D (PDB: 5CA1) alongside with the solved NZO complex (Native) and the docked complex (Docked).
| Drug | Protein (5CA1) subunit B | Protein (5CA1) subunit D |
|---|---|---|
| NZO (native) |
|
|
| NZO (docked) |
|
|
| Mebendazole |
|
|
| Albendazole |
|
|
| Ciclobendazole |
|
|
| Fenbendazole |
|
|
| Flubendazole |
|
|
| Oxibendazole |
|
|
| Oxfendazole |
|
|
| Thiabendazole |
|
|
| Bendazole |
|
|