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. 2021 Mar 24;12:627130. doi: 10.3389/fneur.2021.627130

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Copyright © 2021 Peihong, Tao, Zhaoxuan, Sha, Li, Kunnan, Jingwen, Likai, Yuke, Yuyi, Fumin, Zilei, Ruirui and Fang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Brain regions showed the overlap nodal characteristics of significant difference; (B) The differences in nodal topological properties between FC and HS. The marks (*) indicated statistically significant differences between the two groups (P < 0.05, FDR corrected). (C) The correlations between duration and the nodal betweenness of left thalamus in patients with FC. FC, Functional constipation; HS, Health Subjects; The abbreviations of the 90 brain regions were given in Supplementary Materials.