Table 2.
The significant differences of nodal characteristics existed in between group.
| Brain regions | Category | Nodal betweenness Mean ± SD | Nodal degree Mean ± SD | Nodal efficiency Mean ± SD | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| FC | HS | P | FC | HS | P | FC | HS | P | ||
| FC>HS | ||||||||||
| Frontal_Sup_Orb_L | Paralimbic | 27.83 ± 16.53 | 16.40 ± 14.07 | 0.0002* | 3.64 ± 0.80 | 2.83 ± 1.03 | 0.0003* | 0.124 ± 0.008 | 0.117 ± 0.012 | 0.0001* |
| Frontal_Sup_Orb_R | Paralimbic | 0.123 ± 0.007 | 0.116 ± 0.013 | 0.0003* | ||||||
| Frontal_Mid_Orb_R | Paralimbic | 11.72 ± 8.99 | 5.64 ± 6.20 | 0.0036* | 2.64 ± 0.72 | 1.86 ± 0.95 | 0.0001* | 0.117 ± 0.009 | 0.108 ± 0.012 | 0.0000* |
| Cingulum_Ant_L | Paralimbic | 2.74 ± 0.46 | 2.13 ± 0.63 | 0.0000* | 0.117 ± 0.006 | 0.113 ± 0.009 | 0.0008* | |||
| Cingulum_Ant_R | Paralimbic | 14.12 ± 6.21 | 7.88 ± 5.42 | 0.0000* | 2.74 ± 0.46 | 2.05 ± 0.62 | 0.0000* | 0.119 ± 0.006 | 0.113 ± 0.008 | 0.0000* |
| ParaHippocampal_R | Paralimbic | 2.24 ± 0.51 | 1.97 ± 0.42 | 0.0067* | ||||||
| Amygdala_R | Subcortical | 0.098 ± 0.007 | 0.093 ± 0.010 | 0.0005* | ||||||
| Lingual_R | 2.82 ± 0.63 | 2.54 ± 0.60 | 0.0071 | |||||||
| Pallidum_R | Subcortical | 1.55 ± 0.59 | 1.16 ± 0.63 | 0.0014* | 0.108 ± 0.009 | 0.102 ± 0.010 | 0.0013* | |||
| Temporal_Pole_Sup_L | Association | 3.46 ± 0.81 | 2.92 ± 0.82 | 0.0026* | 0.121 ± 0.008 | 0.115 ± 0.009 | 0.0003* | |||
| Temporal_Pole_Sup_R | Association | 0.119 ± 0.007 | 0.113 ± 0.010 | 0.0002* | ||||||
| FC < HS | ||||||||||
| Frontal_Mid_R | Association | 1.80 ± 0.52 | 2.23 ± 0.66 | 0.0004* | ||||||
| Rectus_R | Paralimbic | 5.56 ± 4.35 | 11.14 ± 8.18 | 0.0002* | ||||||
| Paracentral_Lobule_L | Association | 7.33 ± 3.98 | 12.42 ± 10.01 | 0.0022 | 2.23 ± 0.53 | 2.65 ± 0.75 | 0.0029* | |||
| Caudate_L | Subcortical | 13.18 ± 10.11 | 26.84 ± 16.64 | 0.0000* | 2.62 ± 0.65 | 3.21 ± 0.79 | 0.0020* | 0.118 ± 0.008 | 0.124 ± 0.008 | 0.0003* |
| Caudate_R | Subcortical | 2.53 ± 0.68 | 3.10 ± 0.73 | 0.0058* | ||||||
| Thalamus_L | Subcortical | 25.27 ± 14.64 | 38.92 ± 17.53 | 0.0000* | 3.30 ± 1.02 | 3.87 ± 0.68 | 0.0018* | 0.126 ± 0.011 | 0.132 ± 0.007 | 0.0011* |
| Thalamus_R | Subcortical | 17.86 ± 11.15 | 27.85 ± 15.37 | 0.0030* | ||||||
FC, Functional Constipation group; HS, Healthy Subjects group. The abbreviations of the 90 brain regions are given in Supplementary Materials.
*
The marker indicated a significant difference in FC group and HS group. P < 0.05, FDR corrected.
The bold black font denotes that differences existed in the three nodal characteristics simultaneously.