Table 2.
Designs of 85 interventional trials registered with ClinicalTrial.gov.
| Characteristics | Number | Percentage (%) | |
|---|---|---|---|
| Primary purpose | |||
| Diagnosis | 13 | 15.29 | |
| Treatment | 33 | 38.82 | |
| Prevention | 16 | 18.82 | |
| Supportive care | 15 | 17.65 | |
| Health services research | 6 | 7.06 | |
| Unknown | 2 | 2.35 | |
| Intervention | |||
| Behavioral | 21 | 24.71 | |
| Device | 28 | 32.94 | |
| Diagnostic test | 6 | 7.06 | |
| Procedure | 7 | 8.24 | |
| Other | 23 | 27.06 | |
| Intervention model | |||
| Parallel assignment | 53 | 62.35 | |
| Factorial assignment | 1 | 1.18 | |
| Crossover assignment | 3 | 3.53 | |
| Single group assignment | 24 | 28.24 | |
| Sequential assignment | 3 | 3.53 | |
| Unknown | 1 | 1.18 | |
| Allocation | |||
| Randomized | 59 | 69.41 | |
| Nonrandomized | 11 | 12.94 | |
| N/A | 14 | 16.47 | |
| Unknown | 1 | 1.18 | |
| Masking | |||
| Single | 20 | 23.53 | |
| Double | 8 | 9.41 | |
| Triple | 2 | 2.35 | |
| Quadruple | 2 | 2.35 | |
| None (open-label) | 52 | 61.18 | |
| Unknown | 1 | 1.18 | |
| Enrollment | |||
| 0–100 | 39 | 45.88 | |
| 100–500 | 22 | 25.88 | |
| >500 | 24 | 28.23 | |
| Gender | |||
| Both | 84 | 98.82 | |
| Female | 1 | 1.18 | |
| Participant age (year) | |||
| <18 | 8 | 9.41 | |
| ≥18 | 63 | 74.12 | |
| Both | 14 | 16.47 | |
| Status | |||
| Not recruiting | 9 | 10.59 | |
| Recruiting | 15 | 17.65 | |
| Completed | 46 | 54.12 | |
| Suspended | 1 | 1.18 | |
| Terminated/withdrawn | 7 | 8.24 | |
| Unknown | 7 | 8.24 | |
| Results | |||
| Has results | 10 | 11.76 | |
| No results available | 75 | 88.24 | |
| Sponsor | |||
| University | 43 | 50.59 | |
| Hospital | 25 | 29.41 | |
| Industry/company | 8 | 9.41 | |
| Other | 9 | 10.59 | |
| Funding source | |||
| Industry | 8 | 9.41 | |
| Other | 77 | 90.59 | |
| Location | |||
| America | 42 | 49.41 | |
| Europe | 28 | 32.94 | |
| Asia | 4 | 4.71 | |
| Australia | 4 | 4.71 | |
| Unknown | 7 | 8.24 | |