Table 2.
Crude association between nodular features and malignant risk of GGN.
| Characteristics | Statistics | OR (95%CI) | P-value |
|---|---|---|---|
| Age (years) | 60.2 ± 8.9 | 1.055 (1.004–1.109) | 0.034 |
| Age group (years) | 0.035 | ||
| <60 | 81 (42.2%) | 1.0 | |
| ≥60 | 111 (57.8%) | 2.690 (1.070–6.761) | |
| Gender | 0.005 | ||
| Female | 131 (68.2%) | 1.0 | |
| Male | 61 (31.8%) | 0.272 (0.109–0.679) | |
| Smoking history | 36 (18.8%) | 0.345 (0.132–0.900) | 0.030 |
| GGN number | 0.524 | ||
| Single | 110 (57.3%) | 1.0 | |
| Multiple | 82 (42.7%) | 1.349 (0.538–3.385) | |
| Nodule type | 0.789 | ||
| pGGN | 66 (34.4%) | 1.0 | |
| mGGN | 126 (65.6%) | 0.878 (0.339–2.273) | |
| Location | 0.988 | ||
| Periphery | 186 (96.9%) | 1.0 | |
| Center | 6 (3.1%) | 2099572.789 (0.000-Inf) | |
| Shape | 0.402 | ||
| Round/quasi-round | 115 (59.9%) | 1.0 | |
| Irregular | 77 (40.1%) | 1.500 (0.581–3.870) | |
| Margin | 0.199 | ||
| Smooth | 106 (55.2%) | 1.0 | |
| Lobulated | 86 (44.8%) | 1.860 (0.722–4.793) | |
| Abnormal air bronchogram | 139 (72.4%) | 1.983 (0.793–4.958) | 0.143 |
| Vacuolar sign | 29 (15.1%) | 0.776 (0.242–2.484) | 0.669 |
| Pleura indentation | 111 (57.8%) | 11.032 (3.139–38.780) | <0.001 |
| Vascular convergence | 179 (93.2%) | 1.445 (0.299–6.995) | 0.647 |
| DGGN | 18.9 ± 6.7 | 1.068 (0.997–1.144) | 0.063 |
| Dsolid | 7.0 ± 6.5 | 1.028 (0.958–1.104) | 0.437 |
| CTR | 0.3 ± 0.3 | 0.592 (0.134–2.619) | 0.490 |
| CTR (0.5) | 0.606 | ||
| CTR ≤0.5 | 123 (64.1%) | 1.0 | |
| CTR >0.5 | 69 (35.9%) | 0.788 (0.318–1.950) | |
| CTR (0.25) | 0.402 | ||
| CTR ≤0.25 | 77 (40.1%) | 1.0 | |
| CTR >0.25 | 115 (59.9%) | 0.667 (0.258–1.720) | |
| CTGGO | −462.8 ± 132.3 | 1.001 (0.997–1.004) | 0.733 |
| ΔCTGGO-LP | 398.1 ± 122.6 | 1.000 (0.997–1.004) | 0.888 |
| SUV index | 1.1 ± 1.0 | 0.547 (0.377–0.795) | 0.002 |
The results are expressed as mean ± (SD)/N (%).
Inf: the model failed because of the small sample size.
pGGN, pure ground-glass nodule; mGGN, mixed ground-glass nodule; DGGN, diameter of the GGN; Dsolid, diameter of the solid component; CTR, Dsolid/DGGN; CTGGO, attenuation value of the GGO component on CT; ΔCTGGO-LP, CTGGO - CTLP; SUV index, GGN SUVmax/liver SUVmean.