Table 2.

Vital parameters at baseline and during treatment with placebo or ivabradine.

Vital parameters	Baseline	Placebo	Ivabradine	p-value Placebo vs Ivabradine
Heart rate, bpm	79.7 ± 7.2	70.2 ± 8.3	58.8 ± 8.2	< 0.0001
Systolic BP, mmHg	137.9 ± 18.4	141.5 ± 17.8	144.4 ± 22.1	0.49
Diastolic BP, mmHg	80.1 ± 11.5	82.2 ± 10.7	79.4 ± 11.6	0.22

Data are presented as the mean value ± standard deviation. Values for ivabradine and placebo are given as pooled analysis, regardless of whether patients received ivabradine or placebo first or after cross-over. BP, blood pressure; bpm, beats per minute.