Table 1.
Demographic and neuropsychological data.
| Items | HC (n = 22) | MCI (n = 43) | p-valuea |
|---|---|---|---|
| Demographic Data | |||
| Age (years) | 73.77 (5.00) | 74.22 ± 2.82 | 0.644 |
| Education (years) | 16.27 ± 2.05 | 15.66 ± 2.53 | 0.333b |
| Sex (male/female) | 7/15 | 21/22 | 0.111c |
| Neuropsychological Data | |||
| CDRSB | 0.02 (0) | 1.66 (2) | <0.001 |
| ADAS11 | 5.38 (4) | 9.88 (7) | <0.001 |
| ADAS13 | 8.62 (4) | 15.93 (11) | <0.001 |
| ADASQ4 | 2.76 (2) | 5.44 (4) | <0.001 |
| MMSE | 28.9 (2) | 27.8 (3) | 0.01 |
| MoCA | 25.48 (3) | 22.9 (4) | 0.001 |
| RAVLT: Immediate recall | 47.38 (14) | 33.59 (13) | <0.001 |
| RAVLT: Learning | 6.29 (4) | 3.98 (5) | 0.001 |
| RAVLT: Forgetting | 3.29 (2) | 4.85 (3) | 0.024 |
| RAVLT: Percent Forgetting | 28.25 (21.47) | 63.11 (52.91) | <0.001 |
| LDELTOTAL | 14.67 (4) | 6.78 (4) | <0.001 |
| TRABSCOR | 89.29 (31) | 107.85 (74) | 0.024 |
| FAQ | 0.5 (0) | 3.88 (8) | <0.001 |
| ECogPT: Memory | 1.6 (0.5) | 2.14 (0.94) | 0.001 |
| ECogPT: Langue | 1.31 (0.44) | 1.86 (0.82) | 0.002 |
| ECogPT: Visual-spatial | 1.17 (0.29) | 1.45 (0.79) | 0.017 |
| ECogPT: Planning | 1.08 (0.2) | 1.47 (0.8) | <0.001 |
| ECogPT: Organization | 1.17 (0.42) | 1.46 (0.67) | 0.039 |
| ECogPT: Divided attention | 1.52 (0.63) | 1.78 (0.75) | 0.064 |
| ECogPT: Total score | 1.31 (0.29) | 1.73 (0.79) | <0.001 |
Note: values with normal distributions are presented as the mean ± standard deviation (SD); values with nonnormal distributions are presented as the median (interquartile). χ2 test was applied in the comparisons of sex. One-way Kruskal-Wallis test was applied in age and all neuropsychological data comparisons. aMonte Carlo significant. bThe p-value was obtained by one-way ANOVA. cThe p-value was obtained by χ2 test. Abbreviations: HC, healthy control; MCI, mild cognitive impairment; CDRSB, Clinical Dementia Rating Scale: sum of boxes; ADAS, Alzheimer’s Disease Assessment Scale cognitive subscales; MMSE, Mini-Mental State Examination; MoCA, Montreal Cognitive Assessment; RAVLT, Rey Auditory Verbal Learning Test; LDELTOTAL, Logical Memory Test: total number of units recalled; TRABSCOR, Trail Making Test-B; FAQ, Functional Activities Questionnaire; ECogPT, Everyday Cognition test: the patient reported version.