Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 19;15(4):1024–1039. doi: 10.1002/1878-0261.12813

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 The Authors. Published by FEBS Press and John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Fig. 5 — Clonal relatedness and decomposition of the epithelial and mesenchymal components of metaplastic breast carcinomas and uterine carcinosarcomas. (A) Clonality index of the epithelial and mesenchymal components of metaplastic breast cancers (MBCs, left) and of the epithelial and mesenchymal components of uterine carcinosarcomas (UCSs, right) subjected to WES based on somatic mutations. The histologic components are clonally related in all cases. (B) Cancer cell fractions (CCFs) of the somatic mutations identified in the epithelial and mesenchymal histologic components by WES in the metaplastic breast carcinoma MP15, (C) in the UCS CS4, and (D) UCS CS8. Mutations are grouped by their CCF as inferred by pyclone [44]. Cluster memberships are depicted below the heatmaps, and the corresponding phylogenetic trees are displayed. The length of the trunk and branches represent the number of shared and private somatic mutations identified in the different histologic components.