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. 2021 Mar;13(3):1684–1696. doi: 10.21037/jtd-20-1550

Table 1. General characteristics of included studies.

Author (year) Country Sample Enrolling period Exposure detection Outcome measure Asthma/wheeze assessment Pregnancy trimester Effect size NOS score
Source Period
Berger K (2019) (17) California, USA 329 1999–2000 Urine Prenatal Asthma Questionnaires NA aOR 8
Buckley JP (2018) (18) New York, USA 404 1998–2002 Urine Prenatal Asthma Questionnaires NA aOR 8
Vernet C (2017) (19) Nancy/Poitiers, France 587 NA Urine Prenatal Asthma wheeze Questionnaires NA aHR 8
Wang IJ (2016) (22) Taiwan, China 453 NA Urine Postnatal Asthma Questionnaires NA aOR 8
Gascon M (2015) (20) Catalonia, Spain 654 2004–2008 Urine Prenatal Asthma wheeze Questionnaires NA aRR 8
Spanier AJ (2014) (25) Ohio, USA 398 2003–2006 Urine Prenatal
postnatal
Wheeze Questionnaires 16 weeks
26 weeks
aOR 8
Kim KN (2014) (23) Seoul, Korea 127 2005–2009 Urine Postnatal Asthma wheeze Questionnaires NA aOR 8
Donohue KM (2013) (24) New York,USA 568 1998–2006 Urine Prenatal postnatal Asthma wheeze Wheeze by questionnaires at 5,6,7y and asthma by physicians once between 5y and 12y. NA aOR 9
Spanier AJ (2012) (21) Ohio, USA 365 2003–2006 Urine serum Prenatal Asthma wheeze Questionnaires and ige levels 16 weeks;
26 weeks
aOR 8

All studies were designed as cohort studies. BPA, Bisphenol A; NA, not available; aOR, adjusted odds ratio; aRR, adjusted rate ratio; aHR, adjusted hazard ratio; NOS, the New Castle-Ottawa Scale for cohort studies.