(A) Kaplan–Meier curves of Th17 cells in immune cells. Genetic analysis of the TCGA and GEO databases showed that the high-invasion group had a significant inhibitory effect on the prognosis of COAD, and Th17 cells were associated with a better prognosis (GEO samples: P=0.009, HR = 5.79, 95% CI: 1.55−21.6, TCGA samples: P=0.001, HR = 3.11, 95% CI: 1.57−6.15). (B) Forrest plot of univariate Cox regression analysis in COAD (Th17 cells were associated with prognosis and HR < 1, both as protective factors in both TCGA and GEO).