Table 2.

Brain regions demonstrating significant AUDIT, AUDIT-by-Explore, CUDIT-by-NP, and CUDIT-by-NP-by-Explore effects.

Coordinates of Peak Activationb
Regiona	Hemisphere	BA	x	y	z	F	Partial η2	Voxels
Main Effect of AUDIT
Ventral Putamenc	R	–	26	14	−1	17.20	0.124	11
dlPFC	R	9/10	29	50	26	17.55	0.127	26
dlPFC	L	10/46	−37	44	5	17.27	0.125	24
dlPFC	L	9/10	−22	44	26	16.17	0.118	16
aIC/iFG	R	22/45/ 47/13	53	−1	2	31.02	0.204	117
aIC/iFG	L	32	−46	20	11	22.99	0.160	48
iFG	R	11	38	35	−10	24.85	0.170	21
Precentral Gyrusc	L	6	−55	2	29	20.69	0.146	13
Supramarginal Gyrus/iPL	L	40	−49	−49	32	17.10	0.124	23
Cerebellum	R	–	32	−52	−37	25.29	0.173	19
Cerebellum	L	–	−31	−49	−28	26.92	0.182	38
Thalamusc	R	–	29	−19	2	19.19	0.137	15
AUDIT-by-Explore
Caudate	L	–	−16	5	14	16.08	0.117	20
Ventral Putamen/aIC/iFG	R	47	47	17	2	25.17	0.172	79
aIC/iFG	L	45	−46	20	11	18.29	0.131	23
dlPFC	L	10/46	−37	44	5	18.43	0.132	26
ACCc	L	32	−10	35	17	16.29	0.119	13
MFG	R	47	35	32	−4	20.71	0.146	21
iPLc	L	40	−49	−52	35	15.42	0.110	16
CUDIT-by-NP
iPL	R	40	47	−40	38	21.04	0.148	39
Cerebellum	R/L	–	5	−76	−28	19.78	0.141	19
CUDIT-by-NP-by-Explore
dmPFC	R/L	32	2	20	41	14.73	0.109	21
iPL	R	40	47	−40	38	20.46	0.145	31
Superior Temporal Gyrus	R	13	59	−43	17	16.53	0.120	25

Note:

^aAccording to the Talairach Daemon Atlas (http://www.nitrc.org/projects/tal-daemon/).

^bBased on the Tournoux & Talairach standard brain template.

^cBelow the ClustSim established threshold, BA = Brodmann’s Area.