Table 2.
Listing of Down-Regulated Proteins in Cancer Cell–PSC Grafted Mice Plasma: SOM230 vs Untreated
| Protein name | Log ratio SOM230/NT |
|---|---|
| CD14 | -0.836393 |
| IFN-γ | -0.257125 |
| TIM-1 | -0.2522933 |
| IL5 | -0.2357543 |
| Chemerin | -0.2076414 |
| PDGF-BB | -0.2058304 |
| IL10 | -0.2005681 |
| Leptin | -0.1993592 |
| Serpin F1 | -0.1981243 |
| Flt-3 ligand | -0.1887131 |
| CD160 | -0.1865666 |
| CXCL9 | -0.1772411 |
| TNF-α | -0.1492109 |
| Myeloperoxidase | -0.1471288 |
| Pentraxin 2 | -0.1347746 |
| E-selectin | -0.1293948 |
| IL12p40 | -0.121981 |
| FGF acidic | -0.1169429 |
| IL13 | -0.1077902 |
| LDL R | -0.1072964 |
| VCAM-1 | -0.1065818 |
| IL11 | -0.09950715 |
| PD-ECGF | -0.09708886 |
| M-CSF | -0.09599823 |
| RBP4 | -0.095954 |
| LIF | -0.09346522 |
| PCSK9 | -0.09068561 |
| CCL11 | -0.08666945 |
| IL1 α | -0.08475557 |
| IGFBP-3 | -0.08151417 |
| IL27p28 | -0.0749929 |
| CXCL11 | -0.07498571 |
| RAGE | -0.06808221 |
| CXCL10 | -0.05732954 |
| Pentraxin 3 | -0.05685075 |
| Endoglin | -0.05549461 |
| IL7 | -0.05403424 |
| Pref-1/DLK-1 | -0.0525299 |
| P-selectin | -0.05165642 |
| IGFBP-5 | -0.04817382 |
| IL15 | -0.04627419 |
| Periostin | -0.04173948 |
| Lipocalin-2 | -0.03777582 |
| IL28 | -0.03427079 |
| Osteopontin | -0.033357 |
| IL33 | -0.02293778 |
| IL4 | -0.02049208 |
| IL6 | -0.01649792 |
NOTE. Pool of n = 5 mice/group.
CCL, CC chemokine ligand; CXCL, (C-X-C) motif ligand; DLK-1, delta-like protein 1; FGF, fibroblast growth factor; Flt-3, fms like tyrosine kinase 3; IFN, interferon; IGFBP, insulin-like growth factor- binding protein; IL, interleukin; LDL, low-density lipoprotein; LIF, leukemia inhibitory factor; PCSK9, proprotein convertase subtilisin/kexin type-9; PD-ECGF, platelet-derived endothelial cell growth factor; PDGF-BB, platelet-derived growth factor-BB; RAGE, receptor for advanced glycation end products; RBP-4, retinol-binding protein 4; TIM-1, T cell Ig and mucin 1; TNF, tumor necrosis factor; VCAM-1, vascular cell adhesion molecule 1.