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. 2021 Apr 7;34(4):991–998. doi: 10.1007/s40620-021-01036-8

Table 2.

Biological parameters at admission and CT-scan reports in the two groups of patients (hyponatremic or normonatremic)

Missing values, N (%) Hyponatremic (n = 92) Missing values N (%) Normonatremic (n = 198) p
Biological parameters
 Creatinine (µM) 0 (0) 89 ± 39 1 (0.5) 92 ± 47 0.7121
 Lymphocyte counts* (× 109 /l) 2 (2) 0.87 [0.61–1.18] 11 (6) 0.96 [0.71–1.454] 0.108
 ALT* (UI/l) 21 (23) 38 [25–72] 33 (17) 30 [20–45] 0.009
 AST* (UI/l) 21 (23) 54 [42–83] 35 (18) 38 [27–55] < 0.001
 Fibrinogen* (g/l) 49 (53) 5.0 [4.2–7.4] 96 (48) 4.6 [4.1–6.4] 0.093
 C-Reactive protein* (mg/l) 30 (32) 66 [31–130] 43 (22) 40 [11–85] 0.040
 Troponin* (ng/l) 32 (34) 13 [8–28] 84 (42) 17 [9–35] 0.186
 Creatine Kinase* (UI/l) 40 (43) 124 [63–302] 89 (45) 96 [55–223] 0.344
 d-dimer* (ng/ml) 67 (72) 716 [454–1244] 142 (72) 608 [377–988] 0.236
CT-scan
 Thoracic CT-scan performed (n/%) 48 (52) 75 (38)
 CT-scan < 30% lesions (n/total n, %) 9 (19) 33 (44) 0.010
 CT-scan: 30–50% lesions (n/total n, %) 22 (46) 28 (37)
 CT-scan: > 50% lesions (n/total n, %) 17 (35) 14 (19)

Main biological parameters at admission including known prognostic markers and extension of SARS CoV-2 lesions on CT-scans are reported. Extension of lesions was classified into three groups (< 30%, 30–50%, > 50%). Missing values are indicated

Results are expressed as mean ± standard deviation (SD) or median [Inter Quartile Range] for quantitative variables, and comparability between groups was evaluated by Student’s T or non parametric Wilcoxon test (*). p value is indicated for each test (p < 0.05 was considered significant)

Results are expressed with number of patients/percentage for qualitative variables, and comparability between groups was evaluated by Pearson’s Chi-2 test with chi-2 > 3.84 considered significant