Figure 1.

Induction of apoptosis by the combination of EGCG and resveratrol. (A) SqCCy1, (B) MDA686Tu and (C) Tu212 cells were treated with various doses of EGCG, resveratrol and their combination as indicated for 72 h. Apoptosis was measured by Annexin V-PE staining. Total apoptosis was determined by combining early and late apoptotic cells. Results from triplicate treatments are presented with standard deviations as error bars. *P<0.05 indicates statistically significant increase in apoptosis when compared with the corrsponding untreated control. EGCG, epigallocatechin gallate. X-axes indicate concentrations (µM) of resveratrol (left-hand panels), EGCG (middle panels). Right panels: Combination of EGCG and resveratrol as indicated in the images.