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. 2020 Jan 10;13(8):749–763. doi: 10.4155/fmc-2019-0274

Figure 3. . Fluorescent chemical probes demonstrate cellular target engagement.

Figure 3. 

UNC1215 was tagged with the cell penetrant, long wavelength merocyanine dye mero76 and mero76-UNC1215 was shown to colocalize with GFP-L3MBTL3, indicating that UNC1215 engages its target in cells. Localization of mero76-UNC1215 was perturbed with the addition of untagged UNC1215.