Table 1.

Mean percentages (mean ± standard deviation) of FoxP3⁺CD4⁺ cells in total CD4⁺ cells, of IFN-γ⁺CD4⁺ cells in total CD4⁺ cells, and of IFN-γ⁺CD8⁺ cells in total CD8⁺ cells in different groups of 183 oral lichen planus (OLP) patients and 20 healthy control subjects.

Patient group	FoxP3+CD4+ cells (%)	IFN-γ+CD4+ cells (%)	IFN-γ+CD8+ cells (%)
OLP patients (n = 183)	4.9 ± 2.4	16.8 ± 10.1	46.0 ± 21.9
aP-value	0.464	0.211	0.001
EOLP patients (n = 148)	4.9 ± 2.1	17.4 ± 10.3	46.8 ± 22.2
aP-value	0.406	0.141	<0.001
bP-value	0.658	0.113	0.285
Major EOLP patients (n = 67)	5.4 ± 1.9	20.7 ± 10.2	57.9 ± 19.9
aP-value	0.049	0.006	<0.001
bP-value	0.568	0.003	<0.001
cP-value	0.008	<0.001	<0.001
Minor EOLP patients (n = 81)	4.5 ± 2.1	14.7 ± 9.7	37.6 ± 19.8
aP-value	1.000	0.728	0.086
bP-value	0.249	0.875	0.236
NEOLP patients (n = 35)	5.1 ± 3.4	14.4 ± 8.8	42.4 ± 20.2
aP-value	0.451	0.826	0.017
OLP patients (n = 183)
61–80 year (n = 62)	4.8 ± 2.2	17.2 ± 10.1	52.0 ± 21.2
aP-value	0.563	0.175	<0.001
dP-value	0.852	0.418	<0.001
eP-value	0.452	0.856	0.102
41–60 year (n = 99)	5.1 ± 2.6	16.9 ± 10.3	46.3 ± 21.5
aP-value	0.316	0.214	0.001
dP-value	0.499	0.478	<0.001
20–40 year (n = 22)	4.7 ± 2.0	15.2 ± 9.3	27.8 ± 15.4
aP-value	0.700	0.606	0.761
Healthy control subjects (n = 20)`	4.5 ± 1.2	13.9 ± 6.5	29.3 ± 16.3

EOLP = erosive OLP; NEOLP = non-erosive OLP.

^aComparisons between any OLP group patients and healthy control subjects by Student's t-test.

^bComparisons between EOLP, major EOLP, or minor EOLP patients and NEOLP patients by Student's t-test.

^cComparison between major EOLP and minor EOLP patients by Student's t-test.

^dComparisons between 61 and 80 year or 41–60 year OLP patients and 20–40 year OLP patients by Student's t-test.

^eComparison between 61–80 year and 41–60 year OLP patients by Student's t-test.