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. 2021 Jan 5;16(2):608–613. doi: 10.1016/j.jds.2020.12.009

Table 1.

Comparisons of mean corpuscular volume (MCV), mean blood concentrations of hemoglobin (Hb), iron, vitamin B12, folic acid, and homocysteine between 68 burning mouth syndrome (BMS) patients with microcytosis (MCV < 80 fL) or 816 BMS patients without microcytosis and 442 healthy control subjects as well as between 68 BMS patients with microcytosis and 816 BMS patients without microcytosis.

Group MCV (fL) Hb (g/dL)
Iron (μg/dL)
Vitamin B12 (pg/mL) Folic acid (ng/mL) Homocysteine (μM)
Men Women Men Women
BMS patients with microcytosis (n = 68) 70.9 ± 5.6 13.2 ± 1.0 (n = 11) 11.5 ± 1.1 (n = 57) 89.6 ± 45.8 (n = 11) 67.5 ± 37.5 (n = 57) 631.1 ± 265.9 11.8 ± 6.5 8.7 ± 3.9
aP-value <0.001 <0.001 <0.001 0.103 <0.001 0.033 <0.001 0.190
bP-value <0.001 <0.001 <0.001 0.727 <0.001 0.786 0.003 0.266



BMS patients without microcytosis (n = 816) 91.2 ± 4.8 14.7 ± 1.4 (n = 201) 13.2 ± 1.1 (n = 615) 92.5 ± 25.5 (n = 201) 91.3 ± 30.4 (n = 615) 640.3 ± 268.4 14.6 ± 7.4 9.3 ± 4.3
aP-value 0.002 0.007 <0.001 <0.001 0.001 <0.001 0.805 <0.001



Healthy control subjects (n = 442) 90.4 ± 3.6 15.1 ± 0.8 (n = 106) 13.5 ± 0.7 (n = 336) 105.2 ± 28.0 (n = 106) 97.8 ± 27.2 (n = 336) 694.2 ± 220.2 14.7 ± 5.7 8.3 ± 2.0
a

Comparisons of means of parameters between 68 BMS patients with microcytosis or 816 BMS patients without microcytosis and 442 healthy control subjects by Student's t-test.

b

Comparisons of means of parameters between 68 BMS patients with microcytosis and 816 BMS patients without microcytosis by Student's t-test.